[南昌市艾滋病患者感染的患病率及危险因素]

[Prevalence and risk factors of infections among AIDS patients in Nanchang City].

作者信息

Hu Z H, Chen H H, Qian K, Ning C Q, Peng G H, Yu Y F, Zhou X F, Chu Y H, Xu D, Chen J X, Tian L G, Li H

机构信息

Research Base of the National Key Laboratory of Infectious Disease Prevention and Control, Key Laboratory of Animal Origin and Vector-borne Infectious Diseases of Jiangxi Province, Nanchang Center for Disease Control and Prevention, Jiangxi Province, Nanchang 330038, China.

National Institute of Parasitic Disease, Chinese Center for Disease Control and Prevention, Chinese Center for Tropical Disease Research, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Key Laboratory of Parasites and Vector Biology, National Health Commission, China.

出版信息

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2020 Nov 23;32(6):577-583. doi: 10.16250/j.32.1374.2020208.

DOI:10.16250/j.32.1374.2020208

PMID:33325191

Abstract

OBJECTIVE

To investigate the prevalence and risk factors of infections among AIDS patients in Nanchang City.

METHODS

A cross-sectional questionnaire survey was conducted among AIDS patients in Nanchang City during the period between May and September, 2016. infection was detected in patients'stool samples using a PCR assay, and the CD4 T cell count was measured in subjects'blood samples. In addition, the risk factors of infection in AIDS patients were identified using univariate and multivariate logistic regression analyses.

RESULTS

A survey was conducted in Nanchang City from May to September 2016. A total of 505 AIDS patients were investigated, and the prevalence of infection was 4.16%. Univariate analysis revealed that infection correlated with the occupation ( = 8.595, = 0.049), education level ( = 14.494, = 0.001), type of daily drinking water ( = 10.750, = 0.020), root of HIV infections ( = 8.755, = 0.026) and receiving anti-HIV therapy ( = 23.083, = 0.001) among AIDS patients, and multivariate logistic regression analysis identified daily direct drinking of tap water as a risk factor of infections [odds ratio () = 7.988, 95% confidential interval (): (1.160, 55.004)] and anti-HIV therapy as a protective factor of infection [ = 0.183, 95% : (0.049, 0.685)].

CONCLUSIONS

The prevalence of is 4.16% among AIDS patients in Nanchang City. Daily direct drinking of tap water is a risk factor, and anti-HIV therapy is a protective factor of infection among AIDS patients living in Nanchang City.

摘要

目的

调查南昌市艾滋病患者中[某种感染]的患病率及危险因素。

方法

2016年5月至9月期间，对南昌市的艾滋病患者进行了横断面问卷调查。采用聚合酶链反应（PCR）检测患者粪便样本中的[某种感染]，并检测受试者血液样本中的CD4 T细胞计数。此外，采用单因素和多因素逻辑回归分析确定艾滋病患者中[某种感染]的危险因素。

结果

2016年5月至9月在南昌市进行了一项调查。共调查了505例艾滋病患者，[某种感染]的患病率为4.16%。单因素分析显示，艾滋病患者中[某种感染]与职业（χ² = 8.595，P = 0.049）、教育程度（χ² = 14.494，P = 0.001）、日常饮用水类型（χ² = 10.750，P = 0.020）、HIV感染途径（χ² = 8.755，P = 0.026）及接受抗HIV治疗（χ² = 23.083，P = （此处原文有误，推测应为P = 0.001））有关，多因素逻辑回归分析确定每日直接饮用自来水是[某种感染]的危险因素[比值比（OR） = 7.988，95%置信区间（CI）：（1.160，55.004）]，抗HIV治疗是[某种感染]的保护因素[OR = 0.183，95% CI：（0.049，0.685）]。