法洛四联症补片环缩术后重度肺动脉瓣反流的危险因素。
Risk factors for severe pulmonary regurgitation after repair of tetralogy of Fallot with transannular patch.
机构信息
Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin Hospital, Bandung, Indonesia.
Integrated Cardiac Service, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia.
出版信息
Cardiol Young. 2020 Dec;30(12):1917-1922. doi: 10.1017/S1047951120003170. Epub 2020 Nov 13.
BACKGROUND
Severe pulmonary regurgitation may result in right ventricular volume overload and decreased right ventricular function. Severe pulmonary regurgitation can be predicted prior to repair of tetralogy of Fallot. The aim of this study was to determine the risk factors for severe pulmonary regurgitation in repaired tetralogy of Fallot with transannular patch.
METHODS
This was a cross-sectional study in 43 patients with repaired tetralogy of Fallot using transannular patch. This study was carried out in Dr. Cipto Mangunkusumo hospital during 2015 to 2018. Participants were followed up for routine examination using echocardiography. We used bivariate and multivariate logistic regression using STATA 12.1 to identify risk factors for severe pulmonary regurgitation in this population.
RESULTS
A total of 43 patients composed of 22 boys and 21 girls with repaired tetralogy of Fallot using transannular patch were enrolled in the study. Median age of participants was 6 years at admission (2.1-18.5 years) and 3.4 years (1-17 years) at repair. Median length of follow-up was 2.1(1-4.3) years. Risk factors associated with severe pulmonary regurgitation after tetralogy of Fallot repair were McGoon ratio > 1.8 (odds ratio = 6.9; 95% confidence interval = 1.6-30) and follow-up duration >1.9 years (odds ratio = 3.6; 95% confidence interval = 0.9-15.2).
CONCLUSION
McGoon ratio > 1.8 and follow-up duration > 1.9 years are associated with severe pulmonary regurgitation after tetralogy of Fallot repair.
背景
严重的肺动脉瓣反流可导致右心室容量超负荷和右心室功能下降。在法洛四联症修复前可以预测严重的肺动脉瓣反流。本研究的目的是确定跨环补片修复法洛四联症后严重肺动脉瓣反流的危险因素。
方法
这是一项在使用跨环补片修复的 43 例法洛四联症患者中的横断面研究。本研究于 2015 年至 2018 年在 Dr. Cipto Mangunkusumo 医院进行。参与者接受了常规超声心动图随访检查。我们使用 STATA 12.1 进行了二变量和多变量逻辑回归，以确定该人群中严重肺动脉瓣反流的危险因素。
结果
共纳入 43 例使用跨环补片修复的法洛四联症患者，其中男 22 例，女 21 例。患者入院时的中位年龄为 6 岁（2.1-18.5 岁），修复时的中位年龄为 3.4 岁（1-17 岁）。中位随访时间为 2.1（1-4.3）年。法洛四联症修复后严重肺动脉瓣反流的危险因素是 McGoon 比值>1.8（比值比=6.9；95%置信区间=1.6-30）和随访时间>1.9 年（比值比=3.6；95%置信区间=0.9-15.2）。
结论
McGoon 比值>1.8 和随访时间>1.9 年与法洛四联症修复后严重肺动脉瓣反流相关。
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