Department of Infectious diseases, the Third Affiliated Hospital to Wenzhou Medical University (Ruian People's Hospital), 108 Wansong Road, Ruian, Wenzhou, 325200, Zhejiang Province, China.
Endocrinology Department, the Third Affiliated Hospital to Wenzhou Medical University (Ruian People's Hospital), Ruian City, Zhejiang Province, 325200, China.
BMC Infect Dis. 2020 Nov 13;20(1):841. doi: 10.1186/s12879-020-05528-z.
Coronavirus disease 2019 (COVID-19) is an emerging viral disease. Here, we report the clinical features, management, and short-term outcomes of COVID-19 patients in Wenzhou, China, an area outside Wuhan.
Patients admitted to the Infectious Diseases Department of Ruian People's Hospital in Wenzhou, from January 21 to February 7, 2020, were recruited. Medical data on epidemiological history, demographics, clinical characteristics, laboratory tests, chest computerized tomography (CT) examination, treatment, and short-term outcomes were retrospectively reviewed. Blood biochemistry and routine tests were examined using standard methods and automatic machines. CT examination was performed several times during hospitalization as necessary.
A total of 67 confirmed COVID-19 cases were diagnosed; 64 (95.4%) were common cases and three (4.5%) were severe cases. The most common symptoms at admission were fever (86.6%), cough (77.6%), productive cough (52.2%), chest distress (17.9%), and sore throat (11.9%), followed by diarrhea (7.4%), headache (7.4%), shortness of breath (6.0%), dizziness (4.5%), muscular soreness (4.5%), and running nose (4.5%). Thirty patients (47.8%) had increased C-reactive protein levels. The CT radiographs at admission showed abnormal findings in 54 (80.6%) patients. The patients were treated mainly by oxygen therapy and antiviral drugs. By March 3, 2020, all 67 patients completely recovered and had negative nucleic acid tests. The patients were discharged from the hospital and transferred to a medical observation isolation center for further observation.
Cases of COVID-19 in Wenzhou are milder and have a better prognosis, compared to those in Wuhan. Timely and appropriate screening, diagnosis, and treatment are the key to achieve good outcomes.
新型冠状病毒病（COVID-19）是一种新兴的病毒性疾病。在这里，我们报告了中国温州 COVID-19 患者的临床特征、治疗和短期结局，该地区位于武汉以外。
我们招募了 2020 年 1 月 21 日至 2 月 7 日期间入住瑞安市人民医院传染病科的患者。回顾性分析了流行病学史、人口统计学、临床特征、实验室检查、胸部计算机断层扫描（CT）检查、治疗和短期结局的医疗数据。血液生物化学和常规检查采用标准方法和自动仪器进行。根据需要在住院期间多次进行 CT 检查。
共诊断出 67 例确诊的 COVID-19 病例；64 例（95.4%）为普通病例，3 例（4.5%）为重症病例。入院时最常见的症状是发热（86.6%）、咳嗽（77.6%）、咳痰（52.2%）、胸闷（17.9%）和咽痛（11.9%），其次是腹泻（7.4%）、头痛（7.4%）、呼吸急促（6.0%）、头晕（4.5%）、肌肉酸痛（4.5%）和流鼻涕（4.5%）。30 例（47.8%）患者 C 反应蛋白水平升高。入院时 CT 影像学显示 54 例（80.6%）患者异常。患者主要接受氧疗和抗病毒药物治疗。截至 2020 年 3 月 3 日，67 例患者均完全康复，核酸检测均为阴性。患者出院后转入医学观察隔离中心进一步观察。
与武汉相比，温州的 COVID-19 病例较轻，预后较好。及时、恰当的筛查、诊断和治疗是取得良好结局的关键。
