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耳硬化症和听骨链中断成人的宽带吸光度模式。

Wideband absorbance pattern in adults with otosclerosis and ossicular chain discontinuity.

作者信息

Karuppannan Arunraj, Barman Animesh

机构信息

Department of Audiology/Prevention of Communication Disorders, All India Institute of Speech and Hearing, Manasagangothri, Mysuru, Karnataka, India.

Department of Audiology, All India Institute of Speech and Hearing, Manasagangothri, Mysuru, Karnataka, India.

出版信息

Auris Nasus Larynx. 2021 Aug;48(4):583-589. doi: 10.1016/j.anl.2020.10.019. Epub 2020 Nov 11.

Abstract

OBJECTIVES

Evidence from previous literature had shown that the use of a single frequency probe tone is not sensitive enough to detect middle ear pathologies, especially related to the ossicles, which hinders accurate diagnosis. The goal of the present study was to compare the outcome of wideband absorbance (WBA) tympanometry and to determine the difference in WBA pattern in adults with otosclerosis and ossicular chain discontinuity.

MATERIALS AND METHODS

Estimated adult cases of otosclerosis (10 ears) and ossicular chain discontinuity (06 ears) along with healthy individuals (10 ears) in the age range of 24 to 48 years (mean age: 38.6 years) were considered for the study. WBA was measured at peak and ambient pressure along with resonance frequency and compared with the data obtained from the healthy individuals to determine the WBA pattern.

RESULTS

Data analysis revealed a distinct WBA pattern showing high absorbance at 750 Hz for ossicular chain discontinuity compared to healthy individuals, whereas the otosclerosis group showed reduced absorbance (p < 0.05) at low frequencies (250 Hz to 1500 Hz). WBA measured at the peak and ambient pressure did not elicit any significant difference across the frequencies. Also, the average WBA tympanogram measured between 375 Hz and 2000 Hz showed a significant difference in ambient pressure only in the otosclerosis group. In comparison to healthy individuals (901 Hz), ossicular chain discontinuity showed a significant reduction in resonance frequency (674 Hz), whereas in cases with otosclerosis had higher resonance frequency (1445 Hz).

CONCLUSIONS AND SIGNIFICANCE

The present study showed different WBA patterns between the groups and the absorbance values were significantly different at the low frequencies. This suggests that WBA has the potential to differentiate ossicles related pathologies from normal and also between the ear with otosclerosis and ossicular chain discontinuity.

摘要

目的

以往文献的证据表明,使用单一频率探测音对检测中耳病变的敏感性不足,尤其是与听小骨相关的病变,这会妨碍准确诊断。本研究的目的是比较宽带吸收率(WBA)鼓室导抗图的结果,并确定耳硬化症和听骨链中断的成人患者WBA模式的差异。

材料与方法

本研究纳入了年龄在24至48岁(平均年龄:38.6岁)的耳硬化症成人患者(10耳)、听骨链中断患者(6耳)以及健康个体(10耳)。在峰值压力和环境压力下测量WBA,并测量共振频率,然后将数据与健康个体的数据进行比较,以确定WBA模式。

结果

数据分析显示,与健康个体相比,听骨链中断患者呈现出独特的WBA模式,在750Hz处吸收率较高,而耳硬化症组在低频(250Hz至1500Hz)时吸收率降低(p<0.05)。在峰值压力和环境压力下测量的WBA在各频率之间未引发任何显著差异。此外,仅在耳硬化症组中,在375Hz至2000Hz之间测量的平均WBA鼓室导抗图在环境压力下显示出显著差异。与健康个体(901Hz)相比,听骨链中断患者的共振频率显著降低(674Hz),而耳硬化症患者的共振频率较高(1445Hz)。

结论及意义

本研究显示不同组之间的WBA模式不同,且低频时的吸收率值存在显著差异。这表明WBA有潜力区分与听小骨相关的病变与正常情况,以及区分耳硬化症和听骨链中断的耳朵。

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