Lubicz S, Kelly A, Field P L, Westlake G W, Buxton B, Connell J L, Clarebrough J K
Open Heart Surgery Unit, University of Melbourne Teaching Hospitals, St Vincent's Hospital, Victoria, Australia.
Aust N Z J Surg. 1987 Sep;57(9):593-7. doi: 10.1111/j.1445-2197.1987.tb01432.x.
A retrospective review of 40 consecutive patients undergoing combined coronary artery bypass grafting (CABG) and unilateral carotid endarterectomy (CEA) was carried out to determine the stroke rate for the procedure. Patients presenting with severe coronary artery disease judged to be at risk of imminent myocardial infarction, who had signs of cerebral ischaemia (70%) or asymptomatic carotid bruits (30%), were investigated for extracranial carotid vascular disease. Patients with severe stenotic carotid lesions associated with high risk coronary artery disease underwent combined CEA/CABG. Three patients had a previous contralateral CEA. The average age of the patients was 62 years, and there were 31 males and nine females. CEA was completed prior to CABG under the same general anaesthetic. There were 24 CEAs on the left and 16 on the right. Six patients suffered a postoperative cerebral ischaemic event (15.4%): a reversible ischaemic neurological deficit in three (7.7%), a transient ischaemic cerebral event in two (5.1%), and a permanent stroke occurred in one (2.6%). Two deaths occurred and both were cardiac related. Combined CEA/CABG in patients with stenotic lesions of the coronary and extra-cranial carotid vascular systems who are at risk of cerebral or myocardial infarction, can be performed with a permanent stroke rate within the published range for either CEA or CABG alone and with a mortality of 5%.
对40例连续接受冠状动脉旁路移植术(CABG)和单侧颈动脉内膜切除术(CEA)的患者进行回顾性研究,以确定该手术的卒中发生率。患有严重冠状动脉疾病且被判定有心肌梗死风险、有脑缺血体征(70%)或无症状颈动脉杂音(30%)的患者,接受颅外颈动脉血管疾病检查。患有与高危冠状动脉疾病相关的严重狭窄性颈动脉病变的患者接受CEA/CABG联合手术。3例患者既往有对侧CEA手术史。患者的平均年龄为62岁,其中男性31例,女性9例。CEA在同一全身麻醉下于CABG之前完成。左侧行CEA手术24例,右侧16例。6例患者发生术后脑缺血事件(15.4%):3例出现可逆性缺血性神经功能缺损(7.7%),2例发生短暂性脑缺血事件(5.1%),1例发生永久性卒中(2.6%)。发生2例死亡,均与心脏相关。对于有脑梗死或心肌梗死风险的冠状动脉和颅外颈动脉血管系统狭窄病变患者,CEA/CABG联合手术的永久性卒中发生率在单独进行CEA或CABG已公布的范围内,死亡率为5%。