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布拉迪斯拉发声明:改善胰腺癌治疗的共识建议。

Bratislava Statement: consensus recommendations for improving pancreatic cancer care.

机构信息

Catalonian Cancer Strategy, Department of Health, Barcelona, Spain; University of Barcelona (IDIBELL), Barcelona, Spain.

Med. Onkologie, Tumorzentrum Hamburg, AK Altona, Hamburg, Germany; European Society of Medical Oncology (ESMO), Lugano, Ticino, Switzerland.

出版信息

ESMO Open. 2020 Nov;5(6):e001051. doi: 10.1136/esmoopen-2020-001051.

Abstract

Pancreatic cancer is one of the most lethal tumours, and it is the fourth cause of cancer death in Europe. Despite its important public health impact, no effective treatments exist, nor are there high-visibility research efforts to improve care. This alarming situation is emblematic of a larger group of cancer diseases, known as neglected cancers. To address the impact of these diseases, the European Commission-supported Innovative Partnership for Action Against Cancer launched a multi-stakeholder initiative to determine key steps that healthcare systems can rapidly implement to improve their response. A working group comprising 20 representatives from European medical societies, patient associations, cancer plan organisations and other relevant European healthcare stakeholders was organised. A consensus process based on the results of different studies, discussion of research outcomes, and development and endorsement of draft statements resulted in 22 consensus recommendations (the Bratislava Statement). The statement argues that substantial improvements can be achieved in patient outcomes by centralising pancreatic cancer care around state-of-the-art reference centres, staffed by expert multidisciplinary teams capable of providing high-quality care. This organisational model requires a specific care framework encompassing primary, palliative and survivorship care, and a policy environment prioritising the use of quality criteria and performance assessments as well as research investments dedicated to prevention, risk prediction, early detection and diagnosis. In order to address the challenges posed by neglected cancers in general and pancreatic cancer in particular, a specific control strategy tailored to this reality is required.

摘要

胰腺癌是最致命的肿瘤之一,也是欧洲癌症死亡的第四大原因。尽管它对公众健康有重大影响,但目前尚无有效的治疗方法,也没有高可见度的研究努力来改善治疗效果。这种令人担忧的情况是一类被称为被忽视癌症的更大癌症疾病群体的代表。为了解决这些疾病的影响,欧盟委员会支持的行动抗癌创新伙伴关系发起了一项多利益相关者倡议,以确定医疗保健系统可以迅速实施的关键步骤,以改善其应对措施。成立了一个由 20 名来自欧洲医学协会、患者协会、癌症计划组织和其他相关欧洲医疗保健利益相关者的代表组成的工作组。一个基于不同研究结果、讨论研究结果以及制定和认可草案声明的共识过程产生了 22 项共识建议(布拉迪斯拉发声明)。该声明认为,通过将胰腺癌护理集中在配备能够提供高质量护理的专家多学科团队的最先进的参考中心周围,可以显著改善患者的预后。这种组织模式需要一个特定的护理框架,包括初级、姑息和生存护理,以及一个优先考虑使用质量标准和绩效评估以及专门用于预防、风险预测、早期检测和诊断的研究投资的政策环境。为了解决一般被忽视癌症和特别是胰腺癌所带来的挑战,需要制定一项针对这一现实的具体控制策略。

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