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A Golgi-associated lipid kinase controls peripheral nerve myelination.

作者信息

Posor York, Haucke Volker

机构信息

Department of Molecular Pharmacology and Cell Biology, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), 13125 Berlin, Germany.

Department of Molecular Pharmacology and Cell Biology, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), 13125 Berlin, Germany;

出版信息

Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):30873-30875. doi: 10.1073/pnas.2021130117. Epub 2020 Nov 13.

DOI:10.1073/pnas.2021130117
PMID:33188090
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7733799/
Abstract
摘要

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本文引用的文献

1
Myelination of peripheral nerves is controlled by PI4KB through regulation of Schwann cell Golgi function.外周神经的髓鞘形成由 PI4KB 通过调节施万细胞高尔基体功能来控制。
Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28102-28113. doi: 10.1073/pnas.2007432117. Epub 2020 Oct 26.
2
Rab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth.肌小管素通过 Rab35 调节脂质周转，抑制 mTORC1 活性并控制髓鞘生长。
Nat Commun. 2020 Jun 5;11(1):2835. doi: 10.1038/s41467-020-16696-6.
3
Schwann-Cell-Specific Deletion of Phosphatidylinositol 4-Kinase Alpha Causes Aberrant Myelination.施旺细胞特异性敲除磷脂酰肌醇 4-激酶α导致异常髓鞘形成。
Cell Rep. 2018 Jun 5;23(10):2881-2890. doi: 10.1016/j.celrep.2018.05.019.
4
BIG1/Arfgef1 and Arf1 regulate the initiation of myelination by Schwann cells in mice.BIG1/Arfgef1 和 Arf1 调节施万细胞在小鼠中的髓鞘形成起始。
Sci Adv. 2018 Apr 4;4(4):eaar4471. doi: 10.1126/sciadv.aar4471. eCollection 2018 Apr.
5
The Oxysterol-Binding Protein Cycle: Burning Off PI(4)P to Transport Cholesterol.Oxysterol-Binding Protein 循环：燃烧 PI(4)P 以运输胆固醇。
Annu Rev Biochem. 2018 Jun 20;87:809-837. doi: 10.1146/annurev-biochem-061516-044924. Epub 2018 Mar 29.
6
Myelination and mTOR.髓鞘形成与 mTOR。
Glia. 2018 Apr;66(4):693-707. doi: 10.1002/glia.23273. Epub 2017 Dec 6.
7
Optimal myelin elongation relies on YAP activation by axonal growth and inhibition by Crb3/Hippo pathway.最佳髓鞘伸长依赖于轴突生长激活 YAP 以及 Crb3/Hippo 通路抑制。
Nat Commun. 2016 Jul 20;7:12186. doi: 10.1038/ncomms12186.
8
Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS.Akt调节外周神经系统中的轴突包裹和髓鞘厚度。
J Neurosci. 2016 Apr 20;36(16):4506-21. doi: 10.1523/JNEUROSCI.3521-15.2016.
9
The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.脑白质营养不良蛋白FAM126A（hyccin）调节质膜上磷脂酰肌醇-4-磷酸（PtdIns(4)P）的合成。
Nat Cell Biol. 2016 Jan;18(1):132-8. doi: 10.1038/ncb3271. Epub 2015 Nov 16.
10
Myelination of the nervous system: mechanisms and functions.神经系统的髓鞘形成：机制与功能。
Annu Rev Cell Dev Biol. 2014;30:503-33. doi: 10.1146/annurev-cellbio-100913-013101.