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合成皮肤用于胫前裂伤的治疗:一项对照临床研究。

Synthaderm in the management of pre-tibial lacerations: a controlled clinical study.

作者信息

Martin A, Kirby N G, Tabone Vassallo M, Glucksman E

机构信息

Department of Accident and Emergency, Guy's Hospital, London, England.

出版信息

Arch Emerg Med. 1987 Sep;4(3):179-86. doi: 10.1136/emj.4.3.179.

Abstract

A clinical study of patients with pre-tibial lacerations at King's College Hospital and Guy's Hospital, London, England, compared a non-adhesive dressing with Synthaderm. Treatment was randomly allocated. At King's College Hospital, deep and superficial lacerations were equally distributed, the median time to healing with Synthaderm was significantly (P less than 0.02) reduced; and the median rate of healing (mm/day) was significantly (P less than 0.01) better. At Guy's Hospital, larger and wider wounds were unequally distributed, with fewer in the control group; in the Synthaderm group, the median rate of healing was increased. In both centres, the clinical impression was that Synthaderm reduced nursing dressing time and a better scar resulted. Synthaderm improved the rate of healing in pre-tibial lacerations.

摘要

在英国伦敦国王学院医院和盖伊医院对胫前裂伤患者进行的一项临床研究中,将一种非粘性敷料与合成皮肤敷料(Synthaderm)进行了比较。治疗是随机分配的。在国王学院医院,深部和浅部裂伤分布均匀,使用合成皮肤敷料愈合的中位时间显著缩短(P<0.02);愈合中位速率(毫米/天)显著更好(P<0.01)。在盖伊医院,较大和较宽的伤口分布不均,对照组较少;在合成皮肤敷料组中,愈合中位速率有所提高。在两个中心,临床印象是合成皮肤敷料减少了护理换药时间,且形成的瘢痕更好。合成皮肤敷料提高了胫前裂伤的愈合速率。

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本文引用的文献

1
ANATOMICAL AND PHYSIOLOGICAL FACTORS IN BELOW-KNEE WOUNDS.膝下伤口的解剖学和生理学因素
Lancet. 1965 Jun 26;1(7400):1362-5. doi: 10.1016/s0140-6736(65)92157-4.
2
Pretibial injuries: a common pitfall.胫前损伤:一个常见的陷阱。
Br Med J (Clin Res Ed). 1983 Feb 12;286(6364):502. doi: 10.1136/bmj.286.6364.502.
3
Pretibial lacerations.胫前裂伤。
Br J Plast Surg. 1973 Apr;26(2):172-5. doi: 10.1016/s0007-1226(73)80013-x.

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