National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research, Shanghai 200025, China; School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai 200025, China; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai 200025, China; WHO Collaborating Centre for Tropical Diseases, Shanghai 200025, China.
Hunan Center for Disease Control and Prevention, Changsha 410005, China.
Acta Trop. 2021 Apr;216:105752. doi: 10.1016/j.actatropica.2020.105752. Epub 2020 Nov 12.
Clonorchiasis is an important food-borne parasitic disease in China because of the popularity in ingesting raw freshwater fish. To explore the epidemiology and determinants of clonorchiasis in children, a cross-sectional survey was implemented in two middle schools in Qiyang county, Hunan province, in southeastern China. Questionnaire survey and fecal examination were implemented. Questionnaires were fed back by 627 students, while stool samples were collected from 557 students, out of which 545 ones also provided questionnaire information. The percentage of students ingesting raw freshwater fish was 40.5% (254/627), while the prevalence with Clonorchis sinensis infection was 18.9% (105/557). Such factors contributed significantly to the students' practice in eating raw freshwater fish including boys, fathers' eating raw freshwater fish, mothers' eating raw freshwater fish, and preparation of raw freshwater fish at home, with an adjusted odds ratio of 1.9 (95% confidence intervals (95% CI): 1.3-2.8), 3.9 (95% CI: 2.3-6.5), 3.0 (95% CI: 1.8-4.8) and 2.8 (95% CI: 1.8-4.5), correspondingly. Ingestion of raw freshwater fish, fathers' eating raw freshwater fish and preparation of raw freshwater fish at home were risk factors of C. sinensis infection in students, and the adjusted odds ratio was 3.2 (95% CI: 1.9-5.5), 2.1 (95% CI: 1.1-3.9) and 1.8 (95% CI: 1.0-3.2), respectively. Thus, clonorchiasis was endemic in the surveyed schools due to the ingestion of raw freshwater fish, which is influenced by family environment. Education should be implemented in schools to promote behavioral change of eating raw freshwater fish.
华支睾吸虫病是中国重要的食源性寄生虫病，因生食淡水鱼而流行。为探索儿童华支睾吸虫病的流行病学及决定因素，在中国东南部湖南省祁阳县的两所中学进行了横断面调查。实施问卷调查和粪便检查。627 名学生反馈了问卷，557 名学生采集了粪便样本，其中 545 名学生还提供了问卷信息。摄入生淡水鱼的学生比例为 40.5%（254/627），华支睾吸虫感染率为 18.9%（105/557）。男孩、父亲吃生淡水鱼、母亲吃生淡水鱼和在家中生食淡水鱼的习惯显著促进了学生吃生淡水鱼的习惯，调整后的比值比为 1.9（95%置信区间[95%CI]：1.3-2.8）、3.9（95%CI：2.3-6.5）、3.0（95%CI：1.8-4.8）和 2.8（95%CI：1.8-4.5）。摄入生淡水鱼、父亲吃生淡水鱼和在家中生食淡水鱼是学生感染华支睾吸虫的危险因素，调整后的比值比分别为 3.2（95%CI：1.9-5.5）、2.1（95%CI：1.1-3.9）和 1.8（95%CI：1.0-3.2）。因此，由于生食淡水鱼的摄入，调查学校的华支睾吸虫病呈地方性流行，受家庭环境影响。应在学校开展教育，促进改变生食淡水鱼的行为。
