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多发性硬化症患者的跌倒恐惧与跌倒:文献综述。

Fear of falling and falls in people with multiple sclerosis: A literature review.

作者信息

Scholz Maria, Haase Rocco, Trentzsch Katrin, Weidemann Marie Luise, Ziemssen Tjalf

机构信息

MS Center, Center of Clinical Neuroscience, Department of Neurology, Carl Gustav Carus University Hospital, University of Dresden, Fetscherstr. 74, 01307 Dresden, Germany.

MS Center, Center of Clinical Neuroscience, Department of Neurology, Carl Gustav Carus University Hospital, University of Dresden, Fetscherstr. 74, 01307 Dresden, Germany.

出版信息

Mult Scler Relat Disord. 2021 Jan;47:102609. doi: 10.1016/j.msard.2020.102609. Epub 2020 Oct 31.

Abstract

INTRODUCTION

Fear of falling (FOF) is a widespread problem affecting about 60% of people with multiple sclerosis (pwMS). Inflammatory lesions in the brain that are caused by the disease result in gait deficits and increase the risk of fall. Falls induce fear of falling and trigger a vicious circle, which in turn increases the likelihood of falling. Objective of this review was to provide an overview of existing research on the effects of FOF and therapy options in multiple sclerosis.

METHODS

A systematic search at Web of Science and PubMed was conducted. The search included the terms (fear of falling) OR (concern about falling) OR (fall anxiety) AND (multiple sclerosis).

RESULTS

In included studies, FOF was measured by different instruments. The Falls Efficacy Scale-International (FES-I) was the most frequently used instrument for pwMS. Patients with a higher FOF score fell more frequently, had lower walking speed, shorter stride length, larger ellipse sway area and a more severe disability. At present, therapeutic offers exist mainly in the field of physiotherapy. For reducing FOF, assisted vibration (d = 0.68), VR (d =0.87) and bicycle training (d = 1.23) were the most effective methods.

CONCLUSION

It is advisable to develop therapies that incorporate both physical and psychological aspects in neurorehabilitation, like in a cognitive behavioral therapy. Moreover, FOF monitoring should be integrated into the clinical routine.

摘要

引言

害怕跌倒(FOF)是一个普遍存在的问题,约60%的多发性硬化症患者(pwMS)受其影响。该疾病引起的脑部炎症性病变会导致步态缺陷并增加跌倒风险。跌倒会引发害怕跌倒的情绪,并形成恶性循环,进而增加跌倒的可能性。本综述的目的是概述关于害怕跌倒对多发性硬化症的影响及治疗方案的现有研究。

方法

在科学网和PubMed上进行了系统检索。检索词包括(害怕跌倒)或(担心跌倒)或(跌倒焦虑)以及(多发性硬化症)。

结果

在纳入的研究中,害怕跌倒通过不同的工具进行测量。国际跌倒效能量表(FES-I)是最常用于多发性硬化症患者的工具。害怕跌倒得分较高的患者跌倒频率更高,步行速度更低,步幅更短,椭圆摆动面积更大,残疾程度更严重。目前,治疗方案主要存在于物理治疗领域。对于减轻害怕跌倒,辅助振动(d = 0.68)、虚拟现实(d = 0.87)和自行车训练(d = 1.23)是最有效的方法。

结论

建议在神经康复中开发结合身体和心理方面的治疗方法,如认知行为疗法。此外,应将害怕跌倒监测纳入临床常规。

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