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腔内真空辅助闭合(E-Vac)治疗术后食管瘘:成功病例系列和文献复习。

Endoluminal vacuum-assisted closure (E-Vac) therapy for postoperative esophageal fistula: successful case series and literature review.

机构信息

General Surgery III, ASST Papa Giovanni XXIII, Bergamo, Italy.

General Surgery I, ASST Papa Giovanni XXIII, Piazza OMS, 1, 24127, Bergamo, Italy.

出版信息

World J Surg Oncol. 2020 Nov 14;18(1):301. doi: 10.1186/s12957-020-02073-6.

DOI:10.1186/s12957-020-02073-6
PMID:33189152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7666449/
Abstract

BACKGROUND

Treatment of esophageal perforations and postoperative anastomotic leaks of the upper gastrointestinal tract remains a challenge. Endoluminal vacuum-assisted closure (E-Vac) therapy has positively contributed, in recent years, to the management of upper gastrointestinal tract perforations by using the same principle of vacuum-assisted closure therapy of external wounds. The aim is to provide continuous wound drainage and to promote tissue granulation, decreasing the needed time to heal with a high rate of leakage closure.

CASES PRESENTATION

A series of two different cases with clinical and radiological diagnosis of esophageal fistulas, recorded from 2018 to 2019 period at our institution, is presented. The first one is a case of anastomotic leak after esophagectomy for cancer complicated by pleuro-mediastinal abscess, while the second one is a leak of an esophageal suture, few days after resection of a bronchogenic cyst perforated into the esophageal lumen. Both cases were successfully treated with E-Vac therapy.

CONCLUSION

Our experience shows the usefulness of E-Vac therapy in the management of anastomotic and non-anastomotic esophageal fistulas. Further research is needed to better define its indications, to compare it to traditional treatments and to evaluate its long-term efficacy.

摘要

背景

食管穿孔和上消化道术后吻合口漏的治疗仍然是一个挑战。近年来,腔内负压封闭(E-Vac)治疗通过应用相同的负压封闭治疗外部伤口的原理,对上消化道穿孔的治疗产生了积极的影响。其目的是提供持续的伤口引流,并促进组织肉芽形成,从而缩短愈合时间,并提高漏口闭合率。

病例介绍

本研究回顾性分析了 2018 年至 2019 年期间在我院确诊为食管瘘的两例不同病例,第一例是食管癌切除术后吻合口漏合并纵隔脓胸,第二例是支气管源性囊肿穿孔入食管腔后缝合处漏,两例均成功采用 E-Vac 治疗。

结论

我们的经验表明,E-Vac 治疗在上消化道吻合口和非吻合口瘘的治疗中是有用的。需要进一步的研究来更好地定义其适应证,将其与传统治疗方法进行比较,并评估其长期疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5bd/7666449/b20d3571b0d3/12957_2020_2073_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5bd/7666449/7a83005082e8/12957_2020_2073_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5bd/7666449/5fb8aa90dd27/12957_2020_2073_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5bd/7666449/9054f03547c7/12957_2020_2073_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5bd/7666449/1be9fd845fe3/12957_2020_2073_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5bd/7666449/b20d3571b0d3/12957_2020_2073_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5bd/7666449/7a83005082e8/12957_2020_2073_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5bd/7666449/5fb8aa90dd27/12957_2020_2073_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5bd/7666449/9054f03547c7/12957_2020_2073_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5bd/7666449/1be9fd845fe3/12957_2020_2073_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5bd/7666449/b20d3571b0d3/12957_2020_2073_Fig5_HTML.jpg

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Results of endoscopic vacuum-assisted closure device for treatment of upper GI leaks.内镜下真空辅助闭合装置治疗上消化道漏的结果。
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Surgical treatment of Boerhaave syndrome in the past, present and future: updated results of a specialised surgical unit.Boerhaave 综合征的过去、现在和未来的外科治疗:专门外科单位的最新结果。
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