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Boerhaave 综合征的过去、现在和未来的外科治疗:专门外科单位的最新结果。

Surgical treatment of Boerhaave syndrome in the past, present and future: updated results of a specialised surgical unit.

机构信息

Department of Surgery, Royal Infirmary of Edinburgh, Scotland, NHS Lothian, UK.

出版信息

Ann R Coll Surg Engl. 2024 Jul;106(6):509-514. doi: 10.1308/rcsann.2024.0020. Epub 2024 Apr 2.

Abstract

INTRODUCTION

Boerhaave syndrome is a rare clinical entity associated with high rates of morbidity and mortality. Early recognition of the symptoms, and identification of the site and extension of the injury are key in improving the prognosis.

METHODS

This study presents data on the mortality, morbidity and length of hospital stay in patients diagnosed with Boerhaave syndrome. The data were retrieved from a prospectively collected database in a single surgical unit between 2012 and 2022. The study makes a comparison with the surgical outcomes of the previous decade.

RESULTS

Some 33 patients were diagnosed with Boerhaave syndrome and were treated surgically between 2012 and 2022 in a specialist upper gastrointestinal surgical unit. All patients underwent standard surgical repair (in-theatre diagnostic endoscopy, T-tube placement through thoracotomy and feeding jejunostomy through laparotomy). The mean size of the defects in the oesophageal lumen was 3.3cm. Delayed presentation was noted for 13 patients (39%); 8 patients (24%) died in hospital, and 19 patients (58%) developed postoperative complications. Mortality was similar to the rate recorded for the 20 patients from the previous decade (24% vs 20%, respectively). The mean length of hospital stay was 41 days, and was comparable to the 35.7 days reported between 1997 and 2011.

CONCLUSIONS

Early and aggressive management of spontaneous oesophageal rupture ameliorates the postoperative recovery and prognosis. The surgical results of our unit were found comparable to the previous decade in the population of patients who were treated surgically.

摘要

介绍

Boerhaave 综合征是一种罕见的临床病症,与高发病率和死亡率相关。早期识别症状以及确定损伤部位和范围对于改善预后至关重要。

方法

本研究提供了在单一外科单位 2012 年至 2022 年期间,经诊断患有 Boerhaave 综合征的患者的死亡率、发病率和住院时间的数据。该研究将数据与前十年的手术结果进行了比较。

结果

在一家专门的上消化道外科单位,2012 年至 2022 年间,共诊断出 33 例 Boerhaave 综合征患者,并进行了手术治疗。所有患者均接受了标准的手术修复(术中诊断性内镜检查、经胸 T 型管放置和经剖腹术放置喂养空肠造口术)。食管腔的平均缺损大小为 3.3cm。13 例(39%)患者出现延迟表现,8 例(24%)患者在医院死亡,19 例(58%)患者发生术后并发症。死亡率与前十年记录的 20 例患者的死亡率相似(分别为 24%和 20%)。平均住院时间为 41 天,与 1997 年至 2011 年期间报告的 35.7 天相当。

结论

自发性食管破裂的早期和积极治疗可改善术后恢复和预后。我们单位的手术结果与前十年接受手术治疗的患者群体相当。

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