[全身照射高剂量快中子后大鼠感觉运动皮层轴突树突突触超微结构的早期变化]
[Early changes in the ultrastructure of axodendritic synapses in the rat sensorimotor cortex following whole-body irradiation with high-dose fast neutrons].
作者信息
Abdrakhmanov A A
出版信息
Biull Eksp Biol Med. 1987 Dec;104(12):734-6.
PMID:3318955
Abstract
Changes in morphometric parameters have been established in axodendritic synapses of sensorimotor cortex of adult mature rats exposed to neutron irradiation. Neutron irradiation dose and summarized dose rate were 10 Gy and 0.35 Gy, respectively. The changes were observed 0.25, 1, 3, 6 and 24 hours after irradiation. The observations suggest an increase in synaptic activity, with the range of irradiation action and functional characteristics decreasing in subsequent time periods.
摘要
在接受中子辐照的成年成熟大鼠感觉运动皮层的轴树突触中，已确定形态计量学参数发生了变化。中子辐照剂量和总剂量率分别为10 Gy和0.35 Gy。在辐照后0.25、1、3、6和24小时观察到这些变化。观察结果表明突触活动增加，在随后的时间段内，辐照作用范围和功能特性减小。
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