IRCCS San Raffaele Scientific Institute, Department of Clinical Neurosciences, Neurology - Sleep Disorders Center, Milan, Italy; "Vita-Salute" San Raffaele University, Faculty of Psychology, Milan, Italy.
IRCCS San Raffaele Scientific Institute, Department of Clinical Neurosciences, Neurology - Sleep Disorders Center, Milan, Italy; "Vita-Salute" San Raffaele University, Faculty of Psychology, Milan, Italy.
Brain Cogn. 2020 Dec;146:105642. doi: 10.1016/j.bandc.2020.105642. Epub 2020 Nov 12.
Rapid Eye Movement (REM) sleep is involved in nightly emotional processing; therefore, its disruption might be associated with an impaired ability of emotional regulation during daytime. Accordingly, the aim of the present study was to evaluate the presence of emotional dysregulation in insomnia patients and to test its correlation with REM sleep features. Forty-six subjects (23 insomnia patients and 23 healthy controls) were enrolled. All subjects underwent an assessment for the evaluation of emotion dysregulation (Difficulties in Emotion Regulation Scale, DERS), sleep quality, insomnia severity, excessive daytime sleepiness, worry, rumination, depressive and anxious symptomatology. Insomnia patients underwent a nocturnal polysomnographic recording to characterize sleep macrostructure and REM sleep microstructure variables. Insomnia patients reported increased values of emotional dysregulation. REM sleep percentage and REM sleep latency significantly correlated with DERS total score, and with the subscales "Lack of Confidence in Emotional Regulation Skills", "Difficulties in Behavioral Control" and "Difficulty in recognizing emotions". Furthermore, positive correlations between REM arousal index and emotion dysregulation were found, whereas REM density negatively correlated with DERS. Our results suggest the presence of a relationship between REM sleep and emotional regulation in insomnia patients.
快速眼动（REM）睡眠参与夜间情绪处理；因此，其中断可能与白天情绪调节能力受损有关。因此，本研究旨在评估失眠患者是否存在情绪失调，并测试其与 REM 睡眠特征的相关性。共纳入 46 名受试者（23 名失眠患者和 23 名健康对照者）。所有受试者均接受了情绪失调评估（情绪调节困难量表，DERS）、睡眠质量、失眠严重程度、日间过度嗜睡、担忧、沉思、抑郁和焦虑症状的评估。失眠患者进行了夜间多导睡眠图记录，以描述睡眠的宏观结构和 REM 睡眠的微观结构变量。失眠患者报告情绪失调增加。REM 睡眠百分比和 REM 睡眠潜伏期与 DERS 总分以及“情绪调节技能缺乏信心”、“行为控制困难”和“难以识别情绪”等分量表显著相关。此外，还发现 REM 唤醒指数与情绪失调之间存在正相关，而 REM 密度与 DERS 呈负相关。我们的研究结果表明，失眠患者的 REM 睡眠与情绪调节之间存在关系。
