Department of Pathology, University of Texas Medical Branch, Galveston, TX.
Department of Pathology, University of Texas Medical Branch, Galveston, TX.
Diagn Microbiol Infect Dis. 2021 Jan;99(1):115228. doi: 10.1016/j.diagmicrobio.2020.115228. Epub 2020 Sep 30.
In this study, 127 sputum/tracheal aspirate specimens were evaluated by a laboratory-developed real-time RT-PCR method and Fusion SARS-CoV-2 assay. These specimens were collected from the patients who have nasopharyngeal swab (NPS) samples being used for SARS-CoV-2 detection previously or simultaneously. The overall agreement was 96% between the lower respiratory tract (LRT) and NPS samples, suggesting that LRT specimens could be an option for patients who develop a productive cough or those receiving invasive mechanical ventilation.
本研究采用实验室开发的实时 RT-PCR 方法和 Fusion SARS-CoV-2 检测试剂盒对 127 份痰/气管吸出物标本进行了评估。这些标本是从先前或同时采集了用于 SARS-CoV-2 检测的鼻咽拭子（NPS）样本的患者中收集的。下呼吸道（LRT）样本与 NPS 样本之间的总体一致性为 96%，这表明对于出现有痰咳嗽或接受有创机械通气的患者，LRT 标本可能是一种选择。
