Department of Rehabilitation Medicine, University of Washington, Seattle, Washington.
Department of Internal Medicine, Jefferson University, Philadelphia, Pennsylvania.
Top Spinal Cord Inj Rehabil. 2020 Summer;26(3):152-156. doi: 10.46292/sci2603-152.
Although most people with spinal cord injury (SCI) are emotionally resilient, as a group they are at increased risk of major depressive disorder. Depression tends to be undertreated in people with SCI, perhaps because depression is mistakenly viewed as an expected reaction to severe disability or is confused with grief. Depression and grief are distinguishable, and the Patient Health Questionnaire-9 is a reliable and valid screen for major depression in this population. Major depression can be treated with antidepressants, especially venlafaxine XR, and with psychotherapy, especially cognitive behavioral therapy, focused on helping the person resume activities that were previously enjoyable or meaningful. Structured exercise also may help relieve depressed mood.
尽管大多数脊髓损伤 (SCI) 患者情绪坚韧，但作为一个群体，他们患重度抑郁症的风险增加。SCI 患者的抑郁倾向于治疗不足，这可能是因为抑郁被错误地视为对严重残疾的预期反应，或者与悲伤混淆。抑郁和悲伤是可区分的，患者健康问卷-9 是该人群中重度抑郁症的可靠和有效筛查工具。重度抑郁症可以用抗抑郁药治疗，特别是文拉法辛 XR，也可以用心理治疗，特别是认知行为疗法，重点帮助患者恢复以前喜欢或有意义的活动。结构化运动也可能有助于缓解抑郁情绪。
