Ros Dimitri, Gianferrara Teresa, Crotti Corrado, Farnetti Erica
Dipartimento di Scienze Chimiche e Farmaceutiche, Università di Trieste, Trieste, Italy.
Unità Operativa di Supporto di Trieste, Istituto Struttura della Materia, Consiglio Nazionale delle Ricerche, Trieste, Italy.
Front Chem. 2020 Oct 9;8:810. doi: 10.3389/fchem.2020.00810. eCollection 2020.
The iron(II) complexes Fe(bpy) (bpy = 2,2'-bipyridine; OTf = CFSO) () and Fe(bpydeg) (bpydeg = , -bis(2-(2-methoxyethoxy)ethyl) [2,2'-bipyridine]-4,4'-dicarboxamide) (), the latter being a newly synthesized ligand, were employed as catalyst precursors for the oxidation of 1-phenylethanol with hydrogen peroxide in water, using either microwave or conventional heating. With the same oxidant and medium the oxidation of glycerol was also explored in the presence of and , as well as of two similar iron(II) complexes bearing tridentate ligands, ., Fe(terpy) (terpy = 2, 6-di(2-pyridyl)pyridine () and Fe(bpa) (bpa = bis(2-pyridinylmethyl)amine) (): in most reactions the major product formed was formic acid, although with careful tuning of the experimental conditions significant amounts of dihydroxyacetone were obtained. Addition of heterocyclic amino acids (, picolinic acid) increased the reaction yields of most catalytic reactions. The effect of such additives on the evolution of the catalyst precursors was studied by spectroscopic (NMR, UV-visible) and ESI-MS techniques.
铁（II）配合物Fe（bpy）（bpy = 2,2'-联吡啶；OTf = CFSO）（）和Fe（bpydeg）（bpydeg = ，-双（2-（2-甲氧基乙氧基）乙基）[2,2'-联吡啶]-4,4'-二甲酰胺）（），后者是一种新合成的配体，被用作在水中用过氧化氢氧化1-苯乙醇的催化剂前体，使用微波或传统加热。在相同的氧化剂和介质中，还研究了在 和 以及两种带有三齿配体的类似铁（II）配合物存在下甘油的氧化反应，即Fe（terpy）（terpy = 2,6-二（2-吡啶基）吡啶（）和Fe（bpa）（bpa = 双（2-吡啶基甲基）胺）（）：在大多数反应中，形成的主要产物是甲酸，尽管通过仔细调整实验条件可以获得大量的二羟基丙酮。添加杂环氨基酸（，吡啶甲酸）提高了大多数催化反应的产率。通过光谱（NMR、紫外可见）和ESI-MS技术研究了这些添加剂对催化剂前体演变的影响。
