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Lysyl Oxidase Inhibition Ablates Sexual Dimorphism of Abdominal Aortic Aneurysm Formation in Mice.

作者信息

Okuyama Michihiro, Jiang Weihua, Javidan Aida, Chen Jeff Zheying, Howatt Deborah A, Yang Lihua, Hamaguchi Mika, Yasugi Takumi, Aono Jun, Vazquez-Padron Roberto Irenardo, Subramanian Venkateswaran

机构信息

Saha Cardiovascular Research Center (M.O., W.J., A.J., J.Z.C., D.A.H., L.Y., V.S.), University of Kentucky, Lexington.

Department of Physiology (J.Z.C., V.S.), University of Kentucky, Lexington.

出版信息

Circulation. 2020 Nov 17;142(20):1993-1995. doi: 10.1161/CIRCULATIONAHA.119.044986. Epub 2020 Nov 16.

DOI:10.1161/CIRCULATIONAHA.119.044986
PMID:33196308
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7678818/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16d3/7678818/9f1da68bd640/nihms-1637643-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16d3/7678818/9f1da68bd640/nihms-1637643-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16d3/7678818/9f1da68bd640/nihms-1637643-f0001.jpg

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本文引用的文献

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Am J Physiol Heart Circ Physiol. 2018 Jun 1;314(6):H1137-H1152. doi: 10.1152/ajpheart.00519.2017. Epub 2018 Jan 19.
2
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Hypertension. 2017 Nov;70(5):959-963. doi: 10.1161/HYPERTENSIONAHA.117.09822. Epub 2017 Sep 25.
3
Transient exposure of neonatal female mice to testosterone abrogates the sexual dimorphism of abdominal aortic aneurysms.
Arterioscler Thromb Vasc Biol. 2023 Sep;43(9):e358-e372. doi: 10.1161/ATVBAHA.123.319122. Epub 2023 Jul 20.
4
Targeting lysyl-oxidase (LOX) may facilitate intramural periarterial drainage for the treatment of Alzheimer's disease.靶向赖氨酰氧化酶（LOX）可能有助于壁内动脉周围引流，以治疗阿尔茨海默病。
Cereb Circ Cogn Behav. 2023 Jun 23;5:100171. doi: 10.1016/j.cccb.2023.100171. eCollection 2023.
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Celastrol Supplementation Ablates Sexual Dimorphism of Abdominal Aortic Aneurysm Formation in Mice.藜芦醇补充消除了小鼠腹主动脉瘤形成的性别二态性。
Biomolecules. 2023 Mar 27;13(4):603. doi: 10.3390/biom13040603.
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Treatment With Small Molecule Inhibitors of Advanced Glycation End-Products Formation and Advanced Glycation End-Products-Mediated Collagen Cross-Linking Promotes Experimental Aortic Aneurysm Progression in Diabetic Mice.小分子抑制剂治疗糖基化终产物形成和糖基化终产物介导的胶原交联可促进糖尿病小鼠实验性主动脉瘤的进展。
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JVS Vasc Sci. 2023 Feb 18;4:100098. doi: 10.1016/j.jvssci.2023.100098. eCollection 2023.
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Regulation of lysyl oxidase in vascular cells: lysyl oxidase as a new player in cardiovascular diseases.血管细胞中赖氨酰氧化酶的调控：赖氨酰氧化酶在心血管疾病中的新作用
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