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神经营养性角膜病变的眼表手术治疗:羊膜、结膜移植、眼睑手术及神经化

Surgical Management of the Ocular Surface in Neurotrophic Keratopathy: Amniotic Membrane, Conjunctival Grafts, Lid Surgery, and Neurotization.

作者信息

Trinh Tanya, Mimouni Michael, Santaella Gisella, Cohen Eyal, Chan Clara C

机构信息

Department of Ophthalmology and Vision Sciences, the University of Toronto, Toronto, ON, Canada .

出版信息

Eye Contact Lens. 2021 Mar 1;47(3):149-153. doi: 10.1097/ICL.0000000000000753.

Abstract

PURPOSE

To review the surgical modalities available to treat Mackie stage 2 and stage 3 neurotrophic keratopathy.

METHODS

Literature review and technique descriptions.

RESULTS

The following procedures are described in detail with accompanying videos: temporary, permanent, and botox-assisted tarsorrhaphy; amniotic membrane transplant; keratoplasty with amniotic membrane and tarsorrhaphy augmentation; Gunderson and conjunctival pedicle flaps; buccal graft transplantation; and neurotization.

CONCLUSION

A variety of surgical options exist to manage neurotrophic keratopathy when medical treatments alone fail to resolve epitheliopathy. Ongoing protection and optimization of the ocular surface health remains crucial to prevent recurrent epithelial breakdown.

摘要

目的

回顾可用于治疗麦基2期和3期神经营养性角膜病变的手术方式。

方法

文献综述及技术描述。

结果

详细描述了以下手术操作并配有视频:临时性、永久性及肉毒杆菌辅助睑裂缝合术;羊膜移植;羊膜联合睑裂缝合术增强的角膜移植术;冈德森瓣和结膜蒂瓣;颊黏膜移植;以及神经化手术。

结论

当单纯药物治疗无法解决上皮病变时,有多种手术选择可用于治疗神经营养性角膜病变。持续保护和优化眼表健康对于预防上皮反复破溃仍然至关重要。

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