Wolf H
Max von Pettenkofer Institute, University of Munich, Federal Republic of Germany.
Experientia. 1987 Dec 1;43(11-12):1189-92. doi: 10.1007/BF01945521.
Molecular biology allowed considerable improvements in diagnostic procedures by production of new and more specific sonds for the detection of traces of viruses, both on the nucleic acid and protein levels, and by determining the immune response of the host to specific antigens. Improvements in sensitivity and improved correlation to the stage of viral disease are already evident from several applications and strongly suggest a broad application of these approaches.
分子生物学通过生产新的、更具特异性的探针，在核酸和蛋白质水平上检测病毒痕迹，并通过确定宿主对特定抗原的免疫反应，使诊断程序有了显著改进。从一些应用中已经明显看出，灵敏度的提高以及与病毒疾病阶段相关性的改善，有力地表明了这些方法将得到广泛应用。
