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夏威夷骨质疏松性髋部骨折的死亡率及其相关因素。

Osteoporotic hip fracture mortality and associated factors in Hawai'i.

机构信息

University of Southern California, Los Angeles, USA.

Hawai'i Pacific Health Research Institute, Honolulu, HI, USA.

出版信息

Arch Osteoporos. 2020 Nov 16;15(1):183. doi: 10.1007/s11657-020-00847-9.

Abstract

UNLABELLED

The 30-day mortality of osteoporotic hip fracture patients ≥ 50 years at Hawai'i Pacific Health (2015-2016) was 4.2%. Mortality increased to 17.1% (1 year), 24.5% (2 years), and 30.1% (3 years). Increased age, male sex, higher CCI score, primary insurance status-Medicare/Medicaid, and lower BMI were associated with increased mortality.

PURPOSE

The objective of this study was to evaluate mortality and factors associated with mortality of osteoporotic hip fracture patients at community hospitals within a large healthcare system in Hawai'i.

METHODS

A retrospective chart review was conducted of 428 patients, ≥ 50 years, and hospitalized for a osteoporotic hip fracture from January 2015 to May 2016 within a large healthcare system in Hawai'i. Patient demographics, comorbidities, and treatment were collected from retrospective chart review. We determined the date of death by review of medical records and online public obituary records. We calculated 30-day, 90-day, 1-year, 2-year, and 3-year mortality after discharge for hip fracture admission. Multivariable logistic regression and proportional hazards regression were used to evaluate associations between variables and the mortality of the patients.

RESULTS

The 30-day and 90-day mortality after admission for hip fracture were 4.2% and 8.6%. One-year mortality, 2-year mortality, and 3-year mortality were 17.1%, 24.5%, and 30.1%, respectively. Through proportional hazards regression, older age (hazard ratio (HR) = 1.06, p < 0.001), high comorbidity load (HR = 1.30, p < 0.001), and primary insurance status-Medicare/Medicaid (HR = 3.78, p = 0.021) were associated with increased mortality, while female sex (HR = 0.54, p < 0.001) and higher BMI (HR = 0.94, p = 0.002) were associated with lower mortality.

CONCLUSION

After admission for osteoporotic hip fracture, the 30-day mortality was 4.2%. At 1 year, 2 years, and 3 years, mortality increased to 17.1%, 24.5%, and 30.1%, respectively. Increased age, male sex, higher Charlson comorbidity index score, primary insurance status-Medicare/Medicaid, and lower body mass index were associated with increased mortality.

摘要

目的

本研究旨在评估在夏威夷大型医疗系统内的社区医院中,骨质疏松性髋部骨折患者的死亡率和与死亡率相关的因素。

方法

对 2015 年 1 月至 2016 年 5 月期间在夏威夷大型医疗系统内因骨质疏松性髋部骨折住院的 428 名年龄≥50 岁的患者进行回顾性病历分析。从病历回顾中收集患者的人口统计学、合并症和治疗情况。我们通过查阅病历和在线公共讣告记录来确定死亡日期。我们计算了髋部骨折入院后 30 天、90 天、1 年、2 年和 3 年的死亡率。多变量逻辑回归和比例风险回归用于评估变量与患者死亡率之间的关联。

结果

髋部骨折入院后 30 天和 90 天的死亡率分别为 4.2%和 8.6%。1 年死亡率、2 年死亡率和 3 年死亡率分别为 17.1%、24.5%和 30.1%。通过比例风险回归,年龄较大(风险比[HR] = 1.06,p<0.001)、合并症负担较高(HR = 1.30,p<0.001)和主要保险状态-医疗保险/医疗补助(HR = 3.78,p=0.021)与死亡率增加相关,而女性(HR = 0.54,p<0.001)和较高的 BMI(HR = 0.94,p=0.002)与死亡率降低相关。

结论

骨质疏松性髋部骨折入院后 30 天死亡率为 4.2%。1 年、2 年和 3 年时,死亡率分别增至 17.1%、24.5%和 30.1%。年龄增加、男性、较高的 Charlson 合并症指数评分、主要保险状态-医疗保险/医疗补助和较低的体重指数与死亡率增加相关。

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