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中国老年人骨质疏松性骨折的患病率:系统评价和荟萃分析。

The prevalence of osteoporotic fractures in the elderly in China: a systematic review and meta-analysis.

机构信息

The Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China.

Orthopedic Traumatology II, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.

出版信息

J Orthop Surg Res. 2023 Jul 27;18(1):536. doi: 10.1186/s13018-023-04030-x.

Abstract

BACKGROUND

Prevalence information is the first step in developing preventive procedures or health services. This study was conducted to systematically evaluate the epidemiology of osteoporotic fractures in Chinese elderly aged ≥ 60 years and to provide evidence-based evidence for the prevention and treatment of osteoporotic fractures.

METHODS

We identified relevant studies by searching the literature published in PubMed, Web of Science, Cochrane Library, Embase, CNKI, Wanfang Data, and VIP databases from the establishment of the database until August 2022. We used a random-effects model to obtain prevalence estimates and identified sources of heterogeneity and comparisons of prevalence among different groups through subgroup analysis and sensitivity analysis.

RESULTS

A total of 29 articles were included in this study, and the prevalence of osteoporosis fractures in elderly Chinese was high (18.9%). The prevalence has increased significantly over the past decade (from 13.2% in 2000-2010 to 22.7% in 2012-2022). The prevalence of osteoporosis is higher in women than in men (18.5% vs 14.3%) and increases with age. The northern region was higher than the southern region (20.3% vs 18.9%), and the spine, hip, and distal forearm were the most common sites of fracture.

CONCLUSION

The prevalence of osteoporotic fractures in the Chinese elderly is 18.9%, and timely prevention and treatment are necessary.

摘要

背景

患病率信息是制定预防措施或卫生服务的第一步。本研究旨在系统评估中国≥60 岁老年人群骨质疏松性骨折的流行病学,为骨质疏松性骨折的预防和治疗提供循证依据。

方法

我们检索了 PubMed、Web of Science、Cochrane Library、Embase、CNKI、万方数据和 VIP 数据库中从数据库建立到 2022 年 8 月发表的相关研究,采用随机效应模型获取患病率估计值,并通过亚组分析和敏感性分析确定异质性来源和不同组间患病率的比较。

结果

共纳入 29 篇文献,中国老年骨质疏松性骨折的患病率较高(18.9%)。过去十年患病率显著上升(2000-2010 年为 13.2%,2012-2022 年为 22.7%)。女性患病率高于男性(18.5% vs 14.3%),且随年龄增长而增加。北方地区高于南方地区(20.3% vs 18.9%),骨折最常见的部位是脊柱、髋部和远端前臂。

结论

中国老年人骨质疏松性骨折的患病率为 18.9%,需要及时预防和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bd0/10373275/de085017926c/13018_2023_4030_Fig1_HTML.jpg

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