Department of Psychology, Drexel University, Philadelphia, PA.
Developmental Neurogenomics Unit, National Institute of Mental Health, Bethesda, MD.
Am J Speech Lang Pathol. 2021 Jan 27;30(1):253-259. doi: 10.1044/2020_AJSLP-20-00054. Epub 2020 Nov 16.
Background Down syndrome (DS) is a disorder characterized by impairments in global cognitive abilities and adaptive function. In addition, individuals with DS demonstrate pronounced speech and language deficits. However, little is known about the linguistic correlates of impaired adaptive functioning in DS. Method Using the Adaptive Behavior Assessment System-Second Edition and the Children's Communication Checklist-Second Edition (CCC-2), this study investigated the unique variance in adaptive skills accounted for by speech and language impairments in individuals with DS ( = 29, = 13.46). Results Pearson correlations revealed that a composite of CCC-2 structural language scales, but not pragmatic language scales, was significantly correlated with the Adaptive Behavior Assessment System-Second Edition Global Adaptive Composite, Conceptual, and Practical domains. Further investigation utilizing hierarchical regression analyses identified only the Speech scale on the CCC-2 as contributing unique variance to the prediction of adaptive behavior scores in the Global Adaptive Composite, Conceptual, and Practical domains. Conclusion Speech impairments may serve as flags to identify children with DS who are at risk for adaptive behavior deficits and reinforce the need for speech-language therapies that focus on speech for these individuals. Supplemental Material https://doi.org/10.23641/asha.13231985.
背景 唐氏综合征(DS)是一种以整体认知能力和适应功能受损为特征的疾病。此外,DS 患者表现出明显的言语和语言缺陷。然而,对于 DS 患者适应功能障碍的语言相关因素知之甚少。方法 使用适应性行为评估系统第二版和儿童沟通检查表第二版(CCC-2),本研究调查了言语和语言障碍在 DS 个体适应性技能中所解释的独特差异(n=29,年龄中位数为 13.46 岁)。结果 Pearson 相关分析显示,CCC-2 结构语言量表的综合评分,而不是语用语言量表的评分,与适应性行为评估系统第二版的全球适应性综合、概念和实践领域显著相关。进一步利用分层回归分析发现,只有 CCC-2 的“Speech”量表对全球适应性综合、概念和实践领域的适应性行为评分具有独特的预测作用。结论 言语障碍可能是识别 DS 儿童适应行为缺陷风险的标志,并强调需要针对这些个体的言语进行言语语言治疗。补充材料 https://doi.org/10.23641/asha.13231985.