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产脂化合物的厚壳虫细胞工厂

Thraustochytrid Cell Factories for Producing Lipid Compounds.

机构信息

School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, 2 Xuelin Road, Qixia District, Nanjing, China.

School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, 2 Xuelin Road, Qixia District, Nanjing, China; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, No. 30 South Puzhu Road, Nanjing, China.

出版信息

Trends Biotechnol. 2021 Jul;39(7):648-650. doi: 10.1016/j.tibtech.2020.10.008. Epub 2020 Nov 13.

Abstract

Thraustochytrids can accumulate over 150 g/l biomass, containing up to 55% lipids, without any genetic modification. Their broad substrate utilization capacity, several effective key metabolic pathways, and a well-developed suite of bioprocess engineering strategies all point toward great promise for the future development of these marine protists.

摘要

厚壳贻贝可以在不进行任何基因改造的情况下积累超过 150 克/升的生物质,其中含有高达 55%的脂质。它们广泛的底物利用能力、几条有效的关键代谢途径以及一套完善的生物工艺工程策略,都为这些海洋原生生物的未来发展带来了巨大的希望。

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