• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Hundreds of thousands of cell generations reveal a treasure chest of genome alterations.

作者信息

Argueso Juan Lucas, Alani Eric

机构信息

Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523;

Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853

出版信息

Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):31567-31569. doi: 10.1073/pnas.2021185117. Epub 2020 Nov 16.

DOI:10.1073/pnas.2021185117
PMID:33199644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7749311/
Abstract
摘要

相似文献

1
Hundreds of thousands of cell generations reveal a treasure chest of genome alterations.数十万次细胞传代表明存在着一个基因组改变的宝库。
Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):31567-31569. doi: 10.1073/pnas.2021185117. Epub 2020 Nov 16.
2
Genomic convergence toward diploidy in Saccharomyces cerevisiae.酿酒酵母基因组向二倍体的趋同演化
PLoS Genet. 2006 Sep 22;2(9):e145. doi: 10.1371/journal.pgen.0020145.
3
Mapping of the rib5 gene in Saccharomyces cerevisiae using UV light as an enhancer of rad52-mediated chromosome loss.
Curr Genet. 1988 Nov;14(5):419-23. doi: 10.1007/BF00521263.
4
Comparative genetics of yeast. Communication 8. Genetics of homothallism in Saccharomyces cerevisiae var. ellipsoideus 28-73.酵母的比较遗传学。通讯8。椭圆酵母变种28 - 73同宗配合的遗传学。
Sov Genet. 1974 May 1;8(3):355-9.
5
Use of disomics in mapping ribosomal RNA genes in Saccharomyces cerevisiae.
J Mol Biol. 1972 Dec 30;72(3):811-7. doi: 10.1016/0022-2836(72)90194-5.
6
Chromosome V loss due to centromere knockout or MAD2-deletion is immediately followed by restitution of homozygous diploidy in Saccharomyces cerevisiae.由于着丝粒敲除或MAD2缺失导致的V号染色体丢失后，酿酒酵母中紧接着会恢复纯合二倍体状态。
Yeast. 2002 Apr;19(6):553-64. doi: 10.1002/yea.859.
7
Chromosome-scale genetic mapping using a set of 16 conditionally stable Saccharomyces cerevisiae chromosomes.使用一组16条条件稳定的酿酒酵母染色体进行染色体规模的遗传图谱绘制。
Genetics. 2008 Dec;180(4):1799-808. doi: 10.1534/genetics.108.087999. Epub 2008 Oct 1.
8
Sporulation in mating type homozygotes of Saccharomyces cerevisiae.酿酒酵母交配型纯合子中的孢子形成。
Heredity (Edinb). 1974 Apr;32(2):241-9. doi: 10.1038/hdy.1974.28.
9
Letter: Location and arrangement of genes coding for ribosomal RNA in Saccharomyces cerevisiae.信件：酿酒酵母中编码核糖体RNA的基因的位置与排列
J Mol Biol. 1973 Oct 5;79(4):735-9. doi: 10.1016/0022-2836(73)90076-4.
10
Random-spore analysis in Saccharomyces.
Hereditas. 1971;69(1):67-76. doi: 10.1111/j.1601-5223.1971.tb02419.x.

本文引用的文献

1
Characterization of systemic genomic instability in budding yeast.在出芽酵母中系统基因组不稳定性的特征。
Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28221-28231. doi: 10.1073/pnas.2010303117. Epub 2020 Oct 26.
2
Genome-wide mapping of spontaneous genetic alterations in diploid yeast cells.二倍体酵母细胞中自发遗传改变的全基因组图谱绘制。
Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28191-28200. doi: 10.1073/pnas.2018633117. Epub 2020 Oct 26.
3
Trajectory and uniqueness of mutational signatures in yeast mutators.酵母突变体中突变特征的轨迹和独特性。
Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24947-24956. doi: 10.1073/pnas.2011332117. Epub 2020 Sep 23.
4
Loss of Heterozygosity and Base Mutation Rates Vary Among Hybrid Strains.杂合子丢失率和碱基突变率在杂交株系中存在差异。
G3 (Bethesda). 2020 Sep 2;10(9):3309-3319. doi: 10.1534/g3.120.401551.
5
Recombination-induced revertant mosaicism in ichthyosis with confetti and loricrin keratoderma.先天性鱼鳞病样红皮病伴胶样小体和层板状鱼鳞病的重组诱导回复突变嵌合体。
J Dermatol Sci. 2020 Feb;97(2):94-100. doi: 10.1016/j.jdermsci.2019.12.013. Epub 2019 Dec 31.
6
DNA double-strand break repair-pathway choice in somatic mammalian cells.体细胞核哺乳动物细胞中 DNA 双链断裂修复途径的选择。
Nat Rev Mol Cell Biol. 2019 Nov;20(11):698-714. doi: 10.1038/s41580-019-0152-0. Epub 2019 Jul 1.
7
The dynamic three-dimensional organization of the diploid yeast genome.二倍体酵母基因组的动态三维组织
Elife. 2017 May 24;6:e23623. doi: 10.7554/eLife.23623.
8
Genetic drift, selection and the evolution of the mutation rate.遗传漂变、选择与突变率的进化。
Nat Rev Genet. 2016 Oct 14;17(11):704-714. doi: 10.1038/nrg.2016.104.
9
Mechanisms and regulation of mitotic recombination in Saccharomyces cerevisiae.酿酒酵母有丝分裂重组的机制与调控
Genetics. 2014 Nov;198(3):795-835. doi: 10.1534/genetics.114.166140.
10
The baker's yeast diploid genome is remarkably stable in vegetative growth and meiosis.面包酵母的二倍体基因组在营养生长和减数分裂过程中非常稳定。
PLoS Genet. 2010 Sep 9;6(9):e1001109. doi: 10.1371/journal.pgen.1001109.