南方一群使用暴露前预防(PrEP)的男男性行为者(MSM)中,因新冠疫情导致的性行为、PrEP依从性及性健康服务可及性的变化
Changes in sexual behavior, PrEP adherence, and access to sexual health services due to the COVID-19 pandemic among a cohort of PrEP-using MSM in the South.
作者信息
Pampati Sanjana, Emrick Kayla, Siegler Aaron J, Jones Jeb
机构信息
Department of Epidemiology, Rollins School of Public Health, Emory University.
出版信息
medRxiv. 2020 Nov 12:2020.11.09.20228494. doi: 10.1101/2020.11.09.20228494.
BACKGROUND
The COVID-19 pandemic has had unforeseen consequences on the delivery of HIV and STD prevention services. However, little is known about how the pandemic has impacted PrEP-using men who have sex with men (MSM).
METHODS
Data come from an online cohort of PrEP-using MSM in the Southern United States from October 2019 to July 2020. Participants were administered ten surveys in total, including one ad hoc survey specifically on COVID-19. We conducted a cross-sectional analysis of this ad hoc survey (n=56) and present changes in sexual behaviors and utilization of and access to sexual health services. Using linear mixed-effects regression models, we also analyzed data from the larger cohort (n=78) and document how sexual behaviors and PrEP use varied longitudinally focusing on three months: February (pre-pandemic), April (early pandemic), and June (later in the pandemic).
RESULTS
A fifth of participants discontinued or changed how often they take PrEP because of COVID-19. A quarter of the cohort documented challenges when attempting to access PrEP, HIV testing, or STD testing. For all sexual behaviors examined longitudinally-number of male sexual partners, anal sex acts, condomless anal sex, oral sex (all measured in the past 2 weeks)-there was a significant decrease from February to April followed by a significant increase from April to June.
DISCUSSION
Our findings suggest reduced access to and utilization of STD and HIV services coupled with a continuation of behaviors which confer STD/HIV risk. Ensuring appropriate delivery of STD/HIV prevention services during this pandemic is imperative.
背景
新冠疫情对艾滋病毒和性传播感染预防服务的提供产生了意想不到的影响。然而,对于疫情如何影响使用暴露前预防药物(PrEP)的男男性行为者(MSM),我们知之甚少。
方法
数据来自2019年10月至2020年7月美国南部使用PrEP的男男性行为者在线队列。参与者总共接受了十次调查,包括一次专门针对新冠疫情的特别调查。我们对这次特别调查(n = 56)进行了横断面分析,并呈现性行为以及性健康服务利用和获取情况的变化。我们还使用线性混合效应回归模型分析了来自更大队列(n = 78)的数据,并记录了性行为和PrEP使用在纵向(重点关注三个月:2月(疫情前)、4月(疫情早期)和6月(疫情后期))是如何变化的。
结果
五分之一的参与者因新冠疫情而停止或改变了服用PrEP的频率。四分之一的队列成员表示在尝试获取PrEP、艾滋病毒检测或性传播感染检测时遇到了困难。对于纵向研究的所有性行为(男性性伴侣数量、肛交行为、无保护肛交、口交(均在过去2周内测量)),从2月到4月显著减少,随后从4月到6月显著增加。
讨论
我们的研究结果表明,性传播感染和艾滋病毒服务的获取和利用减少,同时存在导致性传播感染/艾滋病毒风险的行为持续存在的情况。在这场疫情期间确保适当提供性传播感染/艾滋病毒预防服务至关重要。
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