Department of Home Science, University of Delhi, New Delhi, India.
Department of Home Science, Lakshmibai College, University of Delhi, New Delhi, India.
Obes Rev. 2021 Mar;22(3):e13148. doi: 10.1111/obr.13148. Epub 2020 Nov 16.
Understanding the predictors of weight loss with lifestyle interventions can help to ascertain the probable outcomes of individuals with obesity who undergo such interventions. This systematic review assessed the evidence of predictors of successful weight loss among individuals who are overweight or with obesity undergoing lifestyle interventions. Four electronic databases (PubMed, Cochrane Reviews, PsychInfo and Wiley) were searched to find relevant literature published in the past 20 years. A total of 1351 titles were identified in the initial search, of which 23 studies were finally included. Predictors were synthesized in the domains of socio-demographic factors, anthropometric parameters, psychological and behavioural factors and intervention-based factors. The overall quality of evidence on predictors was then appraised using an adapted GRADE approach. Patient-specific factors such as being male, older in age, having existing cardiometabolic comorbidities and limited fat intake were significantly associated with weight loss success. Amongst intervention specific predictors, greater initial weight loss and higher adherence to lifestyle advice were associated with greater weight loss success. In this review, initial weight loss came out to be as the most important predictor of successful weight loss outcome.
了解生活方式干预减肥的预测因素可以帮助确定接受此类干预的肥胖个体的可能结果。本系统评价评估了超重或肥胖个体接受生活方式干预时成功减肥的预测因素的证据。四个电子数据库（PubMed、Cochrane Reviews、PsychInfo 和 Wiley）被搜索以查找过去 20 年发表的相关文献。在最初的搜索中确定了 1351 个标题，最终纳入了 23 项研究。预测因素在社会人口统计学因素、人体测量参数、心理和行为因素以及基于干预的因素等领域进行了综合。然后使用经过改编的 GRADE 方法评估了预测因素的整体证据质量。患者特定因素，如男性、年龄较大、存在心血管代谢合并症和有限的脂肪摄入，与减肥成功显著相关。在特定于干预的预测因素中，初始体重减轻更多和更遵守生活方式建议与更大的体重减轻成功相关。在本综述中，初始体重减轻是成功减肥结果的最重要预测因素。
