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质子 CT 中的相对阻止本领测量和假体伪影减少。

Relative stopping power measurements and prosthesis artifacts reduction in proton CT.

机构信息

Istituto Nazionale di Fisica Nucleare sezione di Firenze, via G. Sansone 1, Sesto Fiorentino (FI), Italy.

Dipartimento di Scienze dell'Informazione, Università degli Studi di Firenze, via S.Marta 3, Firenze, Italy.

出版信息

Phys Med Biol. 2020 Nov 17;65(22):225012. doi: 10.1088/1361-6560/abb0c8.

Abstract

We present a set-up for proton computed tomography (pCT), composed of a microstrip silicon tracker and a YAG:Ce calorimeter, able to directly measure the relative stopping power (RSP) maps to be used in hadron therapy. The system, tested with an electron density phantom at the Trento proton Therapy Center, is able to correlate measured and expected RSP with discrepancies of the order of 1% or less. Furthermore, pCT tomographies of an anthropomorphous head phantom taken with our device, when compared with x-ray CT images of the same object, evidence a significant reduction of artifacts induced by titanium spinal bone prosthesis and tungsten dental filling.

摘要

我们提出了一种质子计算机断层扫描(pCT)系统,由微带硅探测器和 YAG:Ce 量能器组成,能够直接测量用于强子治疗的相对阻止本领(RSP)图谱。该系统在特伦托质子治疗中心的电子密度模型上进行了测试,能够将测量值与预期值相关联,差异在 1%以内。此外,我们的设备对一个仿人头体模进行的 pCT 断层扫描,与相同物体的 X 射线 CT 图像进行比较,证明了钛脊柱骨假体和钨牙填充物引起的伪影显著减少。

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