帕金森病患者血压和心率的年龄相关性变化。
Age-related changes in blood pressure and heart rates of patients with Parkinson's disease.
机构信息
Department of Neurology, University of Yamanashi, Yamanashi, Japan.
出版信息
J Clin Hypertens (Greenwich). 2021 Jan;23(1):175-178. doi: 10.1111/jch.14096. Epub 2020 Nov 17.
This study evaluated yearly changes in systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rates (HR) for patients with Parkinson's disease (PD). Data were collected for the last 10 years from medical records of 28 PD patients and 30 non-PD patients with other neurological disorders. Age-related changes in each group were analyzed by year using mean values of SBP, DBP, and HR obtained at their bi-monthly visits. In results, PD patients had a gradual decrease in SBP with longer disease duration, and mean SBP significantly decreased from Year 7-11 compared to the mean values for Year 1 (p < .001 or p < .01). In non-PD patients, mean SBP significantly increased from Year 4-11 compared to the mean values for Year 1 (p < .001 or p < .01). This is the first study to report age-related changes of BP in individual patients with PD over 10 years.
本研究评估了帕金森病（PD）患者的收缩压（SBP）、舒张压（DBP）和心率（HR）的年度变化。从过去 10 年的病历中收集了 28 名 PD 患者和 30 名患有其他神经障碍的非 PD 患者的数据。使用每个患者每两个月就诊时的 SBP、DBP 和 HR 的平均值，按年份分析了每个组的年龄相关变化。结果表明，PD 患者的 SBP 随着疾病持续时间的延长而逐渐下降，与第 1 年的平均值相比，第 7-11 年的平均 SBP 显著下降（p<0.001 或 p<0.01）。在非 PD 患者中，与第 1 年的平均值相比，第 4-11 年的平均 SBP 显著升高（p<0.001 或 p<0.01）。这是第一项报告 PD 患者超过 10 年的个体 BP 与年龄相关变化的研究。
Zotero 插件