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翼状胬肉手术中眼表肿瘤的意外发生率。一项回顾性临床及组织病理学报告。

An Unexpected Incidence of Ocular Surface Neoplasia on Pterygium Surgery. A Retrospective Clinical and Histopathological Report.

作者信息

Mejía Luis F, Zapata Melissa, Gil Juan C

机构信息

Department of Ophthalmology, CES University, Medellín, Colombia.

出版信息

Cornea. 2021 Aug 1;40(8):1002-1006. doi: 10.1097/ICO.0000000000002586.

DOI:10.1097/ICO.0000000000002586
PMID:33201056
Abstract

PURPOSE

To report the unexpected finding of ocular surface neoplasia (OSSN) on conjunctival tissue removed during pterygium surgery and subjected to histopathology analysis.

METHODS

This is an observational, descriptive retrospective study in which all the samples removed during surgery between 1997 and 2020 with a clinical diagnosis of pterygium were sent for histopathology analysis in which an unexpected OSSN was found.

RESULTS

There were 461 cases with a preoperative diagnosis of pterygium, with a mean age of 30.14 ± 10.6 years. In this group, there was an unexpected finding of OSSN in 69 cases (14.96%) of the surgical samples, with a mean age of 46 ± 8.2 years (31.86 ± 12.13).

CONCLUSIONS

The unexpected coincidence of pterygium and OSSN is frequent, although varies depending on the geographical location. We recommend performing a histopathology analysis on every pterygium removed.

摘要

目的

报告在翼状胬肉手术中切除的结膜组织经组织病理学分析后意外发现眼表肿瘤(OSSN)的情况。

方法

这是一项观察性、描述性回顾性研究,对1997年至2020年期间手术切除的所有临床诊断为翼状胬肉的样本进行组织病理学分析,其中意外发现了OSSN。

结果

术前诊断为翼状胬肉的病例有461例,平均年龄为30.14±10.6岁。在该组中,手术样本中有69例(14.96%)意外发现OSSN,平均年龄为46±8.2岁(31.86±12.13)。

结论

翼状胬肉与OSSN的意外巧合很常见,尽管因地理位置而异。我们建议对每例切除的翼状胬肉进行组织病理学分析。

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Prevalence of co-existent neoplasia in clinically diagnosed pterygia in a UK population.在英国人群中,临床诊断的翼状胬肉中共存肿瘤的患病率。
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Epstein-Barr Virus, But Not Human Papillomavirus, Is Associated With Preinvasive and Invasive Ocular Surface Squamous Neoplasias in Zambian Patients.
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