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医护人员确诊 2019 冠状病毒病（COVID-19）儿童中严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）感染的继发感染率和家庭聚集性。

Secondary Attack Rate and Family Clustering of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children of Healthcare Workers With Confirmed Coronavirus Disease 2019 (COVID-19).

机构信息

Immunisation and Countermeasures Division, London, United Kingdom.

Thomas Waterfield, Centre For Experimental Medicine, Wellcome Wolfson Institute of Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom.

出版信息

Clin Infect Dis. 2021 Jul 1;73(1):e260-e263. doi: 10.1093/cid/ciaa1737.

DOI:10.1093/cid/ciaa1737
PMID:33201219
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7717200/
Abstract

We measured serum SARS-CoV-2 antibodies in 215 children of healthcare workers to estimate secondary attack rates. Twenty-one families had a parent with confirmed COVID-19. There was strong evidence of family clustering (P < .001): 20/21 (95.2%) children were seropositive in 9 families and none of 23 children in 12 other families.

摘要

我们测量了 215 名医护人员子女的血清 SARS-CoV-2 抗体，以估计二次攻击率。21 个家庭有确诊 COVID-19 的父母。有强有力的家庭聚集证据（P<.001）：在 9 个家庭的 21 名儿童中，有 20 名（95.2%）呈血清阳性，而在 12 个其他家庭的 23 名儿童中均无阳性。

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