Chachia N, Combes A M, Romdane K, Bec P
Service d'Ophtalmologie, Hôpital Universitaire Fattouma Bourguiba, C.H.U. de Monastir, Tunisie.
J Fr Ophtalmol. 1987;10(5):381-6.
The authors studied 33 maculopathies in 54 patients affected by typic retinitis pigmentosa: atrophic macular degeneration 31 cases (49%); cystoïd macular oedema: 1 case (3%) and macular retraction syndrome: 1 case (3%). These results are confronted with those of the literature. Two therapeutical trials based on pathogenical hypothesis were conducted. The patient with cystoïd macular oedema was treated by Hyperbar oxygenotherapy, basing one of selves on the theory ischemia. Six other patients with atrophic foveolopathies were treated by the cyclophosphamide, according to the autoimmune theory. In the first trial, the result was positive. In the second one, the results did not permit any available conclusion.
作者研究了54例典型色素性视网膜炎患者中的33例黄斑病变：萎缩性黄斑变性31例（49%）；黄斑囊样水肿：1例（3%）和黄斑退缩综合征：1例（3%）。这些结果与文献报道的结果进行了对比。基于发病机制假说进行了两项治疗试验。黄斑囊样水肿患者接受了高压氧治疗，其依据是缺血理论。另外6例萎缩性小凹病变患者根据自身免疫理论接受了环磷酰胺治疗。在第一项试验中，结果是阳性的。在第二项试验中，结果无法得出任何有效结论。
