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子宫颈罕见的肠外芽囊原虫病病例。

An Unusual Case of Extra-Enteric Blastocystosis in the Uterine Cervix.

作者信息

Escutia-Guzman Yolanda, Martinez-Flores Williams Arony, Martinez-Ocaña Joel, Martinez-Pimentel Ramon, Benitez-Ramirez Marisol, Martinez-Hernandez Fernando, Arroyo-Escalante Sara, Romero-Valdovinos Mirza, Orozco-Mosqueda Guadalupe Erendira, Maravilla Pablo

机构信息

Coordinacion de Cancer Cervicouterino, Laboratorio Estatal de Salud Publica, Morelia 58270, Michoacan, Mexico.

Hospital General "Dr. Manuel Gea Gonzalez", Mexico City 14080, Mexico.

出版信息

Korean J Parasitol. 2020 Oct;58(5):571-576. doi: 10.3347/kjp.2020.58.5.571. Epub 2020 Oct 22.

Abstract

Extra-enteric infections by Blastocystis spp. have rarely been documented. Here, we report a case of extra-enteric blastocystosis in a patient with minimal cervicitis symptoms. A 47-year-old Hispanic female patient was attended in a primary health centre in Michoacan state, Mexico, for her routine gynaecological medical examination. As only symptom, she referred to a slight vaginal itching. The presence of several vacuolar-stages of Blastocystis spp. were identified by Papanicolaou staining; molecular identification was attempted by culture-PCR sequencing of a region of 18S gene from cervical and faecal samples obtained 2 months after cytological examination, even when patient declared that she tried self-medicating with vaginal ovules. Blastocystis ST1 was identified only in the faecal sample. The presence of Blastocystis spp. in the cervix of a patient with scarce symptomatology, demonstrates the extraordinary flexibility of this microorganism to adapt to new environments and niches.

摘要

芽囊原虫属的肠外感染鲜有文献记载。在此,我们报告一例患有轻微宫颈炎症状患者的肠外芽囊原虫病病例。一名47岁的西班牙裔女性患者在墨西哥米却肯州的一家初级保健中心接受常规妇科体检。她仅提及有轻微的阴道瘙痒这一症状。通过巴氏染色法鉴定出存在多个芽囊原虫属的空泡期;在细胞学检查两个月后,从宫颈和粪便样本中获取18S基因区域进行培养 - PCR测序,尝试进行分子鉴定,即便患者称她曾尝试使用阴道栓剂自行治疗。仅在粪便样本中鉴定出芽囊原虫ST1型。在症状轻微的患者宫颈中存在芽囊原虫属,表明这种微生物具有非凡的适应新环境和生态位的灵活性。

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