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子宫颈亚型的分子鉴定:一项针对波兰患者的研究。

Molecular Identification of Subtypes in the Cervix: A Study on Polish Patients.

作者信息

Suchońska Barbara, Kaczmarek Adam, Wesołowska Maria, Młocicki Daniel, Sałamatin Rusłan

机构信息

1st Department of Obstetrics and Gynaecology, Medical University of Warsaw, 02-015 Warsaw, Poland.

Department of Microbiology and Parasitology, Faculty of Medical Science. Collegium Medicum, Cardinal Stefan Wyszyński University in Warsaw, 01-938 Warsaw, Poland.

出版信息

J Clin Med. 2025 Jun 3;14(11):3928. doi: 10.3390/jcm14113928.

DOI:10.3390/jcm14113928
PMID:40507689
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12156457/
Abstract

: is a common protozoan often found in the gastrointestinal tract of humans. The presence of in the female genital tract-has been reported three times, but the genetic material of the protozoan from this site has been identified only once. : Patients with cervical erosions were enrolled in the study. Samples were collected using dry swabs. DNA was detected using real-time PCR and sequenced. : Thirty patients with cervical erosions were examined. The presence of genetic material was confirmed in nine female patients. subtypes ST1, ST6, and ST7 were recovered from the ectocervix and distal part of the cervical canal of women with large, symptomatic glandular ectopies resistant to standard treatment. In one case, we identified a subtype ST7 in the material from the cervix, which was different from subtype ST3 found in the anus of the same woman. : This observation indicates a possible role for in cervical erosions and suggests that eradication of these organisms may relieve this condition.

摘要

:是一种常见的原生动物,常存在于人类胃肠道中。女性生殖道中存在该原生动物的情况已有三次报道,但仅一次鉴定出该部位原生动物的遗传物质。:研究纳入了宫颈糜烂患者。使用干拭子采集样本。采用实时聚合酶链反应检测并对DNA进行测序。:检查了30例宫颈糜烂患者。9例女性患者中证实存在该原生动物的遗传物质。从对标准治疗有抵抗的、有症状的大的腺性外翻女性的宫颈外口和宫颈管远端分离出了该原生动物的ST1、ST6和ST7亚型。在1例中,我们在来自宫颈的材料中鉴定出一种该原生动物的ST7亚型,其与同一女性肛门中发现的ST3亚型不同。:这一观察结果表明该原生动物在宫颈糜烂中可能起作用,并提示根除这些生物体可能缓解这种状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3284/12156457/98812e7b1cc0/jcm-14-03928-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3284/12156457/98812e7b1cc0/jcm-14-03928-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3284/12156457/98812e7b1cc0/jcm-14-03928-g001.jpg

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One Health. 2024 Jul 22;19:100862. doi: 10.1016/j.onehlt.2024.100862. eCollection 2024 Dec.
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Marked genetic diversity within in Australian wildlife revealed using a next generation sequencing-phylogenetic approach.采用新一代测序-系统发育方法揭示澳大利亚野生动物显著的遗传多样性。
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Division of Blastocystis ST10 into three new subtypes: ST42-ST44.
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J Eukaryot Microbiol. 2024 Jan-Feb;71(1):e12998. doi: 10.1111/jeu.12998. Epub 2023 Sep 1.
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The female reproductive tract microbiotas, inflammation, and gynecological conditions.女性生殖道微生物群、炎症与妇科疾病
Front Reprod Health. 2022 Aug 9;4:963752. doi: 10.3389/frph.2022.963752. eCollection 2022.
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