线粒体和质体中的 RNA 编辑：怪异且广泛存在。

RNA Editing in Mitochondria and Plastids: Weird and Widespread.

机构信息

Institute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice (Budweis), Czech Republic; Faculty of Sciences, University of South Bohemia, České Budějovice (Budweis), Czech Republic.

Institute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice (Budweis), Czech Republic.

出版信息

Trends Genet. 2021 Feb;37(2):99-102. doi: 10.1016/j.tig.2020.10.004. Epub 2020 Nov 14.

DOI:10.1016/j.tig.2020.10.004

PMID:33203574

Abstract

Though widespread, RNA editing is rare, except in endosymbiotic organelles. A combination of higher mutation rates, relaxation of energetic constraints, and high genetic drift is found within plastids and mitochondria and is conducive for evolution and expansion of editing processes, possibly starting as repair mechanisms. To illustrate this, we present an exhaustive phylogenetic overview of editing types.

摘要

尽管 RNA 编辑很普遍，但除了内共生细胞器外，这种现象非常罕见。较高的突变率、能量限制的放松以及高遗传漂变在质体和线粒体中都有发现，这有利于编辑过程的进化和扩展，这些编辑过程可能最初是作为修复机制出现的。为了说明这一点，我们提出了一个详尽的编辑类型系统发育概述。