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支架辅助颅内动脉瘤弹簧圈栓塞的转流技术:一项多中心研究。

Transcirculation approach for stent-assisted coiling of intracranial aneurysms: a multicenter study.

机构信息

Department of Neurosurgery, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA

Department of Neurosurgery, University of Washington School of Medicine, Seattle, WA, USA.

出版信息

J Neurointerv Surg. 2021 Aug;13(8):711-715. doi: 10.1136/neurintsurg-2020-016899. Epub 2020 Nov 17.

DOI:10.1136/neurintsurg-2020-016899
PMID:33203763
Abstract

BACKGROUND

The transcirculation approach (TCA) for stent-assisted coiling (SAC) of intracranial aneurysms may be useful for certain wide-neck bifurcation aneurysms as well as those with acute-angle efferent branches.

OBJECTIVE

To describe a multicenter experience using the TCA for SAC.

METHODS

A multicenter, retrospective study (2016-2020) of aneurysm treatment using SAC via the TCA. Angiographic outcome was scored using the Raymond Scale (adequate occlusion 1 and 2), and clinical outcome was scored using a modified Rankin Scale (good outcome 0-2) RESULTS: Twenty-nine patients with 29 aneurysms were included (62.1% female; average age 61; 89.7% unruptured; 13.8% previously treated; average dome size 6.4 mm; average neck 4.4 mm). Aneurysm locations included internal carotid artery-fetal posterior cerebral artery (n=4), internal carotid artery terminus (n=4), anterior communicating artery (n=8), vertebral artery-posterior inferior cerebellar artery (n=2), and basilar tip (n=11). The TCA used communicating arteries (93.1%; average 1.6 mm), intermediate catheters (51.7%), jailing technique (62.1%), and staged procedures (10.3%). The most common stent was the Neuroform Atlas (Stryker; 69%). Immediate adequate occlusion was obtained in 75.9%, and five patients with inadequate occlusion progressed to adequate occlusion at follow-up. One (3.4%) procedural complication occurred: a watershed stroke in the setting of baseline four-vessel extracranial disease. Two patients had a poor outcome unrelated to the TCA. The majority of patients (86.4%) had a good clinical outcome. One case of in-stent stenosis due to non-compliance with medication was seen, which resolved with medication resumption.

CONCLUSIONS

The TCA for SAC can be performed for a variety of aneurysms with a low complication rate and good clinical outcomes.

摘要

背景

对于某些宽颈分叉动脉瘤以及具有锐角流出分支的动脉瘤,可采用经再循环通路(transcirculation approach, TCA)的支架辅助弹簧圈栓塞术(stent-assisted coiling, SAC)。

目的

描述采用 TCA 行 SAC 的多中心经验。

方法

采用回顾性多中心研究(2016-2020 年),分析采用 TCA 行 SAC 治疗的患者。采用 Raymond 分级(完全闭塞 1 级和 2 级)评估血管造影结果,采用改良 Rankin 量表(改良 Rankin 量表 0-2 级为良好预后)评估临床结果。

结果

共纳入 29 例 29 个动脉瘤患者(女性占 62.1%;平均年龄 61 岁;93.1%未破裂;13.8%为既往治疗;平均瘤颈 4.4mm;平均瘤体 6.4mm)。动脉瘤部位包括颈内动脉-胚胎型大脑后动脉(n=4)、颈内动脉终末段(n=4)、前交通动脉(n=8)、椎动脉-小脑后下动脉(n=2)和基底动脉尖(n=11)。采用再循环通路(93.1%;平均 1.6mm)、中间导管(51.7%)、血管内隔离技术(62.1%)和分期治疗(10.3%)。最常用的支架为 Neuroform Atlas(Stryker)(69%)。即刻完全闭塞率为 75.9%,5 例不完全闭塞患者在随访时进展为完全闭塞。发生 1 例(3.4%)手术并发症:在基线四血管颅外疾病的情况下出现分水岭性卒中。2 例患者预后不良与 TCA 无关。大多数患者(86.4%)临床结局良好。1 例因不遵医嘱服药导致支架内狭窄,恢复服药后狭窄缓解。

结论

TCA 用于 SAC 治疗各种类型的动脉瘤,并发症发生率低,临床结局良好。

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