Ohyama M, Kurokawa T, Kobayashi S, Nakagawa H, Yoshida E, Kobayashi T, Manabe T, Nakajou S
Saiseikai Imabari Hospital.
Gan No Rinsho. 1987 Oct;33(13):1726-32.
An unusual case of a solid and cystic tumor of the pancreas is presented. A 33-year-old woman with a 15-year history of an abdominal tumor underwent a pancreatectomy. The tumor was encapsulated by a thick connective tissue and exhibited two main patterns: solid sheets of relatively uniform small cells; and, a papillary proliferation with a central fibrovascular talk. The tumor cells had PAS and d-PAS reactive granules in the cytoplasm. Immunohistochemically, a positive reaction for alpha l-antitrypsin and a carcinoembryonic antigen, as well as a weekly positive reaction for a vasoactive intestinal polypeptide also were found in the cytoplasm. Our results lead us to suggest that an S-C tumor is likely to be a tumor of a acinar cell origin.
本文报告一例罕见的胰腺实性和囊性肿瘤。一名有腹部肿瘤15年病史的33岁女性接受了胰腺切除术。肿瘤被厚结缔组织包裹,呈现两种主要形态:相对均匀的小细胞实性片;以及伴有中央纤维血管束的乳头状增生。肿瘤细胞在细胞质中有PAS和d-PAS反应性颗粒。免疫组织化学检查发现,细胞质中α1-抗胰蛋白酶和癌胚抗原呈阳性反应,血管活性肠多肽也呈弱阳性反应。我们的结果提示,S-C肿瘤可能起源于腺泡细胞。