Maxillofacial Surgery Trainees Research Collaborative (MTReC), Morriston Hospital, Swansea, SA6 6NL, UK.
Oral Maxillofac Surg. 2021 Sep;25(3):345-349. doi: 10.1007/s10006-020-00922-y. Epub 2020 Nov 17.
Defining current inpatient management of cervicofacial infections is key to identifying strategies to optimise care. Steroid use is beneficial in peritonsillar and orbital abscess, but there are few studies of steroid use in odontogenic cervicofacial infections. Our previous research identified widespread variation in practice, necessitating a national audit to define current practice.
A multicentre, trainee-led snapshot audit was carried out across 25 hospitals in the UK. Information recorded included demographic features, presentation, surgical and medical management, and steroid administration.
One thousand two admissions were recorded. Fifty-five percent were male, with mean age 37.3 years (range 0-94 years). Steroids were administered to 357 patients (36%), 159 of whom received steroids on admission, and 254 peri-operatively. Patients who were prescribed steroids had significantly higher white cell count (12.4 vs 11.5), CRP (79.5 vs 57) and heart rate (94 vs 88) on admission. Justifications given for administration included swelling (74), dysphagia (21), and airway compromise (7). Three patients (0.8%) reported steroid-related side effects.
This study uses the largest recorded cohort of cervicofacial infections to define current inpatient steroid administration. Our results suggest that steroids are targeted towards the most compromised 1/3 of patients. The incidence of steroid-related side effects was low. Defining the characteristics of patients currently receiving steroids will aid in determining whether steroid administration is an effective adjunct in treating odontogenic cervicofacial infection.
明确当前颈面部感染的住院管理对于确定优化治疗策略至关重要。类固醇在扁桃体周脓肿和眼眶脓肿中有益,但在牙源性颈面部感染中,类固醇使用的研究较少。我们之前的研究发现实践中存在广泛的差异,因此需要进行全国性审计以确定当前的实践。
在英国的 25 家医院进行了一项多中心、由受训人员领导的快照审计。记录的信息包括人口统计学特征、表现、手术和药物管理以及类固醇的使用情况。
共记录了 1200 例住院患者。55%为男性,平均年龄为 37.3 岁(范围 0-94 岁)。357 例患者(36%)接受了类固醇治疗,其中 159 例在入院时给予,254 例在围手术期给予。接受类固醇治疗的患者入院时白细胞计数(12.4 比 11.5)、CRP(79.5 比 57)和心率(94 比 88)显著升高。给予类固醇治疗的理由包括肿胀(74 例)、吞咽困难(21 例)和气道阻塞(7 例)。有 3 例(0.8%)患者报告了类固醇相关的副作用。
本研究使用了记录最大的颈面部感染队列来定义当前住院患者的类固醇治疗。我们的结果表明,类固醇主要针对最严重的 1/3 的患者。类固醇相关副作用的发生率较低。确定目前接受类固醇治疗的患者的特征将有助于确定类固醇治疗是否是治疗牙源性颈面部感染的有效辅助手段。