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加拿大温尼伯卫生区家庭接触者中 COVID-19 的继发感染率。

Secondary attack rate of COVID-19 in household contacts in the Winnipeg Health Region, Canada.

机构信息

Winnipeg Regional Health Authority, 490 Hargrave Street, Winnipeg, Manitoba, R3A 0X7, Canada.

出版信息

Can J Public Health. 2021 Feb;112(1):12-16. doi: 10.17269/s41997-020-00451-x. Epub 2020 Nov 17.

Abstract

OBJECTIVES

Understanding important transmission parameters, such as secondary attack rates, can help in strategizing, prioritizing, and planning interventions to curb morbidity and mortality due to COVID-19. Early reports suggest the risk of transmission of SARS-CoV-2 (the pathogen that causes COVID-19 disease) is high among household contacts of cases. The purpose of this analysis was to determine the household transmissibility of SARS-CoV-2 in residents of the Winnipeg Health Region.

METHODS

We extracted information on COVID-19 cases and their household contacts from the regional public health surveillance database and used this dataset to calculate secondary attack rates.

RESULTS

We included 381 individuals from 102 unique households (102 primary cases and 279 household contacts). A total of 41 contacts from 25 households became secondary cases in the 14 days since last unprotected exposure to the primary case, resulting in a secondary attack rate of 14.7% (95% CI: 10.5-18.8).

CONCLUSION

Household transmission of SARS-CoV-2 has been an important contributor to the local COVID-19 epidemic.

摘要

目的

了解重要的传播参数,如二代发病率,有助于制定策略、确定优先事项和规划干预措施,以遏制 COVID-19 导致的发病率和死亡率。早期报告表明,SARS-CoV-2(导致 COVID-19 疾病的病原体)在病例的家庭接触者中传播风险很高。本分析的目的是确定 SARS-CoV-2 在温尼伯卫生区居民中的家庭传播能力。

方法

我们从区域公共卫生监测数据库中提取了 COVID-19 病例及其家庭接触者的信息,并使用该数据集计算了二代发病率。

结果

我们纳入了来自 102 个独特家庭的 381 人(102 个原发性病例和 279 个家庭接触者)。在最后一次与原发性病例无保护接触后的 14 天内,共有来自 25 个家庭的 41 个接触者成为继发性病例,二代发病率为 14.7%(95%CI:10.5-18.8)。

结论

SARS-CoV-2 的家庭传播是当地 COVID-19 疫情的一个重要贡献因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92ed/7851207/bf1da8231570/41997_2020_451_Fig1_HTML.jpg

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