Morton Patricia M, Ferraro Kenneth F
Department of Sociology, Wayne State University, Detroit, MI, USA.
Department of Public Health, Wayne State University, Detroit, MI, USA.
J Health Soc Behav. 2020 Dec;61(4):503-522. doi: 10.1177/0022146520966364. Epub 2020 Nov 18.
We investigate whether childhood exposures influence adult chronic inflammation and mortality risk via adult health characteristics and socioeconomic status (SES) and whether gender moderates these relationships. Analyzing a longitudinal national sample of 9,310 men and women over age 50, we found that childhood SES, parental behaviors, and adolescent behaviors were associated with adult chronic inflammation via health characteristics and SES in adulthood. The process of disadvantage initiated by low childhood SES (i.e., adult health risk factors, socioeconomic disadvantage, and chronic inflammation) subsequently raised mortality risk. In addition, gender moderated the mediating influence of childhood SES via unhealthy behaviors and parental behaviors via adult SES. Demonstrating how social forces shape biological health through multiple mechanisms informs health policies by identifying multiple points of intervention in an effort to reduce the lasting consequences of childhood disadvantage.
我们研究童年时期的经历是否通过成人健康特征和社会经济地位（SES）影响成人慢性炎症和死亡风险，以及性别是否会调节这些关系。通过对9310名50岁以上男性和女性的全国纵向样本进行分析，我们发现童年SES、父母行为和青少年行为通过成年后的健康特征和SES与成人慢性炎症相关。童年SES较低引发的不利过程（即成人健康风险因素、社会经济劣势和慢性炎症）随后增加了死亡风险。此外，性别调节了童年SES通过不健康行为的中介影响，以及父母行为通过成人SES的中介影响。通过识别多个干预点来展示社会力量如何通过多种机制塑造生物健康，为健康政策提供了参考，以努力减少童年劣势的持久影响。
