Department of Epidemiology, University of Washington, 3980 15th Ave NE, Seattle, WA, 98195, USA.
School of Medicine, University of Washington, Seattle, WA, USA.
J Immigr Minor Health. 2021 Dec;23(6):1136-1144. doi: 10.1007/s10903-020-01121-3. Epub 2020 Nov 18.
To examine the relationship between African birth and HIV outcomes and comorbidities among individuals accessing care at the University of Washington. Patients who received a diagnosis of HIV at the University of Washington from 1995 to 2018 were identified. African-born patients were defined as those with recorded birthplace or primary language belonging to an African country. This cohort was compared to all non-African-born patients for initial CD4 count < 200 cells/mL, time from diagnosis to viral suppression, and prevalence of comorbid conditions. We identified 357 African-born and 3710 non-African-born patients. Over the time period, African-born patients were more likely to present with initial CD4 counts < 200 cells/mL (31% vs 19%, p < 0.01), but had shorter time to viral suppression (HR 1.31, [95% CI: 1.14-1.56]). African-born patients had higher rates of hepatitis B and tuberculosis (12% vs. 7% p < 0.01 and 13% vs. 3% p < 0.01). African-born patients living in the Seattle area have better HIV outcomes, but low initial CD4 counts suggest that they are presenting to care late. Increased efforts to engage this population in HIV, hepatitis B, and tuberculosis screening are warranted.
为了考察在华盛顿大学接受治疗的个体中,非洲出生与 HIV 结局和合并症之间的关系。确定了 1995 年至 2018 年期间在华盛顿大学被诊断为 HIV 的患者。将出生地点或主要语言属于非洲国家的患者定义为非洲出生的患者。将该队列与所有非非洲出生的患者进行比较,以评估初始 CD4 计数<200 个细胞/ml、从诊断到病毒抑制的时间以及合并症的流行情况。我们确定了 357 名非洲出生的患者和 3710 名非非洲出生的患者。在研究期间,非洲出生的患者更有可能出现初始 CD4 计数<200 个细胞/ml(31%比 19%,p<0.01),但达到病毒抑制的时间更短(HR 1.31,[95%CI:1.14-1.56])。非洲出生的患者乙型肝炎和结核病的发病率更高(12%比 7%,p<0.01和 13%比 3%,p<0.01)。居住在西雅图地区的非洲出生的患者 HIV 结局较好,但初始 CD4 计数较低,表明他们就诊较晚。需要加强努力,让这一人群参与 HIV、乙型肝炎和结核病的筛查。