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抗锑治疗美国皮肤利什曼病后发生拉姆齐·亨特综合征。

Ramsey hunt syndrome after antimonial treatment for American Cutaneous Leishmaniasis.

机构信息

Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, AM, Brasil.

Universidade do Estado do Amazonas, Programa de Pós-Graduação em Medicina Tropical, Manaus, AM, Brasil.

出版信息

Rev Soc Bras Med Trop. 2020 Nov 13;54:e20200012. doi: 10.1590/0037-8682-0012-2020. eCollection 2020.

DOI:10.1590/0037-8682-0012-2020
PMID:33206873
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7670763/
Abstract

Ramsay Hunt Syndrome (RHS), also known as herpes zoster oticus, is caused by the reactivation of varicella zoster virus (VZV) in the geniculate ganglion of the facial nerve. Herein, we report a case of Ramsey Hunt Syndrome in a patient after antimonial treatment for Cutaneous Leishmaniasis. The patient presented with microvesicles grouped on an erythematous base, starting in the neck and ascending towards the scalp margin on the right side of the head. The patient also developed grade V peripheral facial palsy the day after initiating the herpes zoster treatment, this outcome corroborated the assumption of Ramsey Hunt Syndrome.

摘要

拉姆齐亨特综合征(RHS),也称为带状疱疹性耳炎,是由面神经膝状神经节内水痘带状疱疹病毒(VZV)的再激活引起的。在此,我们报告一例锑剂治疗皮肤利什曼病后发生的拉姆齐亨特综合征病例。患者表现为红斑基础上成群的微疱疹,起始于颈部,向右侧头部头皮边缘上升。患者在开始带状疱疹治疗的第二天出现了Ⅴ级周围性面瘫,这一结果证实了拉姆齐亨特综合征的假设。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b87/7670763/38b95b0869bf/1678-9849-rsbmt-54-e20200012-gf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b87/7670763/70b38664c95b/1678-9849-rsbmt-54-e20200012-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b87/7670763/a1911dced89a/1678-9849-rsbmt-54-e20200012-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b87/7670763/38b95b0869bf/1678-9849-rsbmt-54-e20200012-gf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b87/7670763/70b38664c95b/1678-9849-rsbmt-54-e20200012-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b87/7670763/a1911dced89a/1678-9849-rsbmt-54-e20200012-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b87/7670763/38b95b0869bf/1678-9849-rsbmt-54-e20200012-gf3.jpg

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本文引用的文献

1
Facial paralysis due to Ramsay Hunt syndrome - A rare condition.拉姆齐·亨特综合征所致面瘫——一种罕见病症。
Rev Assoc Med Bras (1992). 2017 Apr;63(4):301-302. doi: 10.1590/1806-9282.63.04.301.
2
Successful response of non-recovering Ramsay Hunt syndrome to intravenous high dose methylprednisolone.静脉注射大剂量甲基强的松龙治疗无恢复的 Ramsay Hunt 综合征有效。
J Neurol Sci. 2012 Jul 15;318(1-2):160-2. doi: 10.1016/j.jns.2012.04.011. Epub 2012 May 4.
3
Prognostic factors in herpes zoster oticus (ramsay hunt syndrome).耳带状疱疹(拉姆齐亨特综合征)的预后因素。
Otol Neurotol. 2011 Aug;32(6):1025-30. doi: 10.1097/MAO.0b013e3182255727.
4
Varicella zoster virus meningitis complicating sodium stibogluconate treatment for cutaneous leishmaniasis.葡萄糖酸锑钠治疗皮肤利什曼病并发水痘带状疱疹病毒脑膜炎
Am J Trop Med Hyg. 2006 Apr;74(4):591-2.
5
Herpes zoster and lymphopenia associated with sodium stibogluconate therapy for cutaneous leishmaniasis.葡萄糖酸锑钠治疗皮肤利什曼病相关的带状疱疹和淋巴细胞减少症。
Clin Infect Dis. 1998 Sep;27(3):509-12. doi: 10.1086/514689.