National Center for Epidemiology, Institute of Health Carlos III, Av/ Monforte de Lemos 5, 28029, Madrid, Spain.
Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.
BMC Geriatr. 2020 Nov 18;20(1):480. doi: 10.1186/s12877-020-01876-2.
Social engagement (SE) has been consistently shown to improve survival among community-dwelling older people, but the evidence in nursing home residents is inconclusive and prone to short-term reverse causation and confounding by major health determinants. Our main objective was to study the potential causal effect of within-the-facility social engagement (SE) on long-term all-cause mortality in care home residents.
A representative cohort of 382 nursing home residents in Madrid without severe physical and cognitive impairments at baseline was followed up for 10-year all-cause mortality. Standardized mortality curves for residents with low/null, moderate, and high levels of SE at baseline were estimated using Kaplan-Meier methods and spline-based survival models with inverse probability of exposure weights conditional on baseline sociodemographic characteristics, facility features, comorbidity, and disability. Standardized 5-year mortality risks and median survival times were compared across levels of SE.
The baseline prevalences of low/null, moderate, and high SE were 36, 44, and 20%, respectively. Compared with residents with low/null SE at baseline, the standardized differences (95% confidence intervals) in 5-year mortality risk were - 2.3% (- 14.6 to 10.0%) for moderately engaged residents and - 18.4% (- 33.8 to - 2.9%) for highly engaged residents. The median survival time increased by 0.4 (- 1.4 to 2.2) and 3.0 (0.8 to 5.2) years, respectively.
Residents with high SE within the nursing home had an 18% lower 5-year mortality risk and a 3-year increase in their median survival, as compared with residents with similar health determinants but low/null SE. The development of adequate tailored intervention programs, addressed to increase SE in nursing home residents, could improve their long-term survival, in addition to expected gains in quality of life.
社会参与(SE)一直被证明可以提高社区居住的老年人的生存率,但在养老院居民中的证据尚无定论,并且容易受到短期反向因果关系和主要健康决定因素的混杂影响。我们的主要目标是研究设施内社会参与(SE)对养老院居民长期全因死亡率的潜在因果效应。
对马德里无严重身体和认知障碍的 382 名养老院居民进行了代表性队列研究,随访时间为 10 年全因死亡率。使用 Kaplan-Meier 方法和基于样条的生存模型,对基线 SE 水平低/无、中、高的居民进行标准化死亡率曲线估计,使用基于暴露概率的逆概率加权,条件为基线社会人口特征、设施特征、合并症和残疾。比较了不同 SE 水平的标准化 5 年死亡率风险和中位生存时间。
基线低/无、中、高 SE 的患病率分别为 36%、44%和 20%。与基线 SE 水平低/无的居民相比,中度参与居民的 5 年死亡率风险标准化差异(95%置信区间)为-2.3%(-14.6 至 10.0%),高度参与居民为-18.4%(-33.8 至-2.9%)。中位生存时间分别增加了 0.4 年(-1.4 至 2.2)和 3.0 年(0.8 至 5.2)。
与具有相似健康决定因素但 SE 水平低/无的居民相比,养老院中 SE 水平高的居民 5 年死亡率风险降低 18%,中位生存时间延长 3 年。制定适当的、有针对性的干预计划,以增加养老院居民的 SE,可以提高他们的长期生存率,除了预期的生活质量提高。