Borromei A, Caramelli R, Cipriani G, Giancola L C, Guerra L, Lozito A
Università di Bologna, Istituto di Clinica Neurologica.
Minerva Med. 1987 Nov 30;78(22):1687-705.
A report is presented on 58 patients (46 males, 12 females) all suffering from post-traumatic epilepsy (PTE) and followed up for a minimum of 1 year to maximum of 23 years after the injury (mean 6.3 years). The type and site of the head injury, the nature of the brain lesions, the time elapsing before the first critical manifestation, the clinical character of the epileptic attacks, EEG, cerebral CAT and RMN data were performed are given for all patients. The therapeutic and prophylactic strategies adopted are then described in detail with particular emphasis on the use of diphenylhydantoin (DPH) and barbexaclone. The latter drug, used for the last 3 years was found to be particularly useful in the treatment of patients suffering from a post-traumatic psycho-organic syndrome in addition to the PTE.
本文报告了58例患者（46例男性，12例女性），均患有创伤后癫痫（PTE），受伤后随访时间最短1年，最长23年（平均6.3年）。给出了所有患者的头部损伤类型和部位、脑损伤性质、首次关键表现出现前的时间、癫痫发作的临床特征、脑电图、脑部计算机断层扫描（CAT）和磁共振成像（RMN）数据。然后详细描述了所采用的治疗和预防策略，特别强调了苯妥英（DPH）和巴比沙隆的使用。发现后一种药物在过去3年中使用，除了对PTE患者外，对患有创伤后精神器质性综合征的患者治疗特别有用。
