Lynch W S, Roenigk H H
Arch Dermatol. 1977 Sep;113(9):1203-8.
Mycophenolic acid is an antimetabolite used experimentally for the treatment of psoriasis. Thirty-eight patients were treated with mycophenolic acid. A double-blind, placebo-controlled study demonstrated the efficacy of mycophenolic acid (P less than .01). A long-term safety study showed the occurrence of hematologic abnormalities, viral infections, and carcinoma. The position of mycophenolic acid in the therapeutic treatment of psoriasis must await the results of a multicenter cooperative study.
霉酚酸是一种抗代谢物，用于银屑病治疗的实验研究。38名患者接受了霉酚酸治疗。一项双盲、安慰剂对照研究证明了霉酚酸的疗效（P<0.01）。一项长期安全性研究显示出现了血液学异常、病毒感染和癌症。霉酚酸在银屑病治疗中的地位必须等待多中心合作研究的结果。
