Debout C, Caillez D, Izard J
Laboratoire d'Histologie, CHU Côte de Nacre, Caen, France.
Pathol Biol (Paris). 1987 Nov;35(9):1249-52.
The exceptional carcinoresistance of guinea-pigs is well known and only a few cases of spontaneous leukaemia and several very rare cases of lymphoma have been reported in the literature. A spontaneous malignant tumor in an old male hybrid guinea-pig is described. The monomorphous aspect of the tumour, the cellular cohesiveness, the "starry-sky" pattern and the immunocytological characterization of tumour cells as B lymphocytes bearing IgM, lead to describe this tumour as a probable spontaneous Burkitt-type malignant lymphoblastic lymphoma.
豚鼠具有特殊的抗癌性，这是众所周知的，文献中仅报道了少数几例自发性白血病和几例非常罕见的淋巴瘤病例。本文描述了一只老年雄性杂种豚鼠身上的自发性恶性肿瘤。肿瘤的单形性、细胞黏附性、“星空”模式以及肿瘤细胞作为携带IgM的B淋巴细胞的免疫细胞特征，使得该肿瘤被描述为可能的自发性伯基特型恶性淋巴细胞淋巴瘤。
