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纳米比亚奥沙纳地区奈韦拉平糖浆用于预防母婴传播的消费时间序列分析及优化供应链模型

Time series analysis of Nevirapine syrup consumption in prevention of mother-tochild transmission and optimal supply chain model in Oshana region, Namibia.

作者信息

Magesa Emmanuel, Mitonga Kabwebwe Honore, Angula Penehafo

机构信息

School of Public Health, University of Namibia, Namibia.

出版信息

J Public Health Afr. 2020 Apr 29;11(1):1029. doi: 10.4081/jphia.2020.1029.

DOI:10.4081/jphia.2020.1029
PMID:33209228
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7649737/
Abstract

HIV/AIDS continue to be serious communicable disease whose impact on public health in Namibia is massive. It is estimated that the prevalence rate of HIV in Namibia is 17.2%, ranking the country as the fifth highest in sub-Saharan Africa (SSA). Some improvement in reducing the number of cases of HIV/AIDS has been made in the country, but the sporadic shortage of medicines continues to slow down government efforts to foster the emergence of an HIVfree generation of Namibians. Develop and demonstrate a mathematical supply-chain model, which can establish parameters to prevent stock-outs of NVP suspension. The study adopted retrospective approach to acquire data from 2012-2016. Gamma supply chain model was developed as the optimal model for NVP syrup and forecasted consumption for 2017-2018 was determined. It is a recommendation of this study that new guidelines for implementation of optimal supply-chain models at the regional medical store, health centers and clinics be implemented for Nevirapine syrup.

摘要

艾滋病毒/艾滋病仍然是一种严重的传染病,对纳米比亚的公共卫生产生了巨大影响。据估计,纳米比亚的艾滋病毒流行率为17.2%,在撒哈拉以南非洲(SSA)排名第五。该国在减少艾滋病毒/艾滋病病例数量方面取得了一些进展,但药品的零星短缺继续减缓政府培育一代无艾滋病毒纳米比亚人的努力。开发并展示一个数学供应链模型,该模型可以建立参数以防止奈韦拉平混悬液缺货。该研究采用回顾性方法从2012年至2016年获取数据。开发了伽马供应链模型作为奈韦拉平糖浆的最优模型,并确定了2017年至2018年的预测消费量。本研究建议为奈韦拉平糖浆在区域医疗商店、健康中心和诊所实施最优供应链模型制定新的指导方针。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c397/7649737/f79921f5d79e/jpha-11-1-1029-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c397/7649737/f79921f5d79e/jpha-11-1-1029-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c397/7649737/f79921f5d79e/jpha-11-1-1029-g001.jpg

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本文引用的文献

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Implementing an Integrated Pharmaceutical Management Information System for Antiretrovirals and Other Medicines: Lessons From Namibia.实施抗逆转录病毒和其他药物的综合药物管理信息系统:来自纳米比亚的经验教训。
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中国湖北基层医疗卫生机构基本药物配送:集中采购安排的影响
BMC Health Serv Res. 2017 Nov 14;17(1):727. doi: 10.1186/s12913-017-2720-3.
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Assessment of the World Health Organization's HIV Drug Resistance Early Warning Indicators in Main and Decentralized Outreach Antiretroviral Therapy Sites in Namibia.纳米比亚主要和分散式外展抗逆转录病毒治疗点的世界卫生组织艾滋病毒耐药性早期预警指标评估
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5
Monitoring HIV and AIDS Related Policy Reforms: A Road Map to Strengthen Policy Monitoring and Implementation in PEPFAR Partner Countries.监测与艾滋病毒和艾滋病相关的政策改革:加强总统防治艾滋病紧急救援计划(PEPFAR)伙伴国家政策监测与实施的路线图。
PLoS One. 2016 Feb 25;11(2):e0146720. doi: 10.1371/journal.pone.0146720. eCollection 2016.
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PLoS One. 2016 Jan 25;11(1):e0147502. doi: 10.1371/journal.pone.0147502. eCollection 2016.
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The study of the optimal parameter settings in a hospital supply chain system in Taiwan.台湾医院供应链系统中最优参数设置的研究。
ScientificWorldJournal. 2014;2014:967140. doi: 10.1155/2014/967140. Epub 2014 Aug 27.
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