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胃肠道肿瘤手术后脓毒症患者的卫生经济评估——中国的成本后果分析

Health economic evaluation of patients with sepsis after gastrointestinal tumor surgery-a cost consequences analysis in China.

作者信息

Chen Ren-Xiong, Wu Zhou-Qiao, Li Zi-Yu, Wang Hong-Zhi, Ji Jia-Fu

机构信息

ICU, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing, China.

Gastrointestinal Cancer Center, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing, China.

出版信息

J Gastrointest Oncol. 2020 Oct;11(5):894-898. doi: 10.21037/jgo-20-242.

Abstract

BACKGROUND

The purpose of this study was to evaluate the health economics of patients with sepsis after gastrointestinal tumor operation in ICU.

METHODS

This case-control study used 1:1 propensity-score (PS) matched method and patients were matched according to tumor type, age and gender. The study group was composed of 181 patients with sepsis after operation of gastrointestinal tumor in ICU, while the control group was composed of 181 patients without sepsis after operation of gastrointestinal tumor. The medical expenses and length of stay in the hospital of these patients were analyzed.

RESULTS

The median of the total hospitalization cost for the study group was $26,038, which was 1.7 times of the control group (P<0.001). The costs of drugs, laboratory test, examination, treatment, operation, anesthesia, materials, ward and other costs in the study group were higher than those in the control group (P<0.001). The median length of stay in the hospital in the study group was 26 days, which were 12 days longer than that of the control group (P<0.001). However, there was no significant difference in daily average cost between the two groups (P=0.103).

CONCLUSIONS

In ICU, patients with sepsis after operation of gastrointestinal tumor increased the cost of hospitalization and prolonged the length of stay in the hospital than those without sepsis.

摘要

背景

本研究旨在评估重症监护病房(ICU)中胃肠道肿瘤手术后脓毒症患者的卫生经济学情况。

方法

本病例对照研究采用1:1倾向评分(PS)匹配法,根据肿瘤类型、年龄和性别对患者进行匹配。研究组由181例ICU中胃肠道肿瘤手术后发生脓毒症的患者组成,而对照组由181例胃肠道肿瘤手术后未发生脓毒症的患者组成。分析了这些患者的医疗费用和住院时间。

结果

研究组总住院费用中位数为26,038美元,是对照组的1.7倍(P<0.001)。研究组的药品、实验室检查、检查、治疗、手术、麻醉、材料、病房及其他费用均高于对照组(P<0.001)。研究组的住院中位时间为26天,比对照组长12天(P<0.001)。然而,两组的日均费用无显著差异(P=0.103)。

结论

在ICU中,胃肠道肿瘤手术后发生脓毒症的患者比未发生脓毒症的患者增加了住院费用并延长了住院时间。

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