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结核性脑膜炎所致双侧完全性动眼神经麻痹

Bilateral Complete Oculomotor Palsy in Tubercular Meningitis.

作者信息

Gaba Saurabh, Gupta Monica, Lamba Amtoj Singh, Bhardwaj Arshia, Gupta Harsheel

机构信息

General Medicine, Government Medical College and Hospital, Chandigarh, IND.

出版信息

Cureus. 2020 Oct 17;12(10):e11001. doi: 10.7759/cureus.11001.

DOI:10.7759/cureus.11001
PMID:33209557
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7669259/
Abstract

A 20-year-old female presented to the emergency department with fever, anorexia, headache, and neck stiffness for two weeks with recent onset of diplopia and ptosis. She was found to have bilateral symmetrical and complete oculomotor palsy. The diagnosis of tubercular meningitis (TBM) was established on magnetic resonance imaging of the brain and cerebrospinal fluid examination. The oculomotor palsy was attributed to tubercular exudates along the ventral surface of midbrain. Although cranial nerves palsies are common in TBM, such a pattern is rarely seen and has been reported only in the context of tuberculoma in midbrain. She was treated with anti-tubercular therapy for nine months, but there was only partial recovery of the oculomotor function.

摘要

一名20岁女性因发热、厌食、头痛和颈部僵硬两周,近期出现复视和上睑下垂,就诊于急诊科。检查发现她患有双侧对称性完全动眼神经麻痹。通过脑部磁共振成像和脑脊液检查确诊为结核性脑膜炎(TBM)。动眼神经麻痹归因于中脑腹侧表面的结核性渗出物。虽然脑神经麻痹在TBM中很常见,但这种模式很少见,仅在中脑结核瘤的情况下有过报道。她接受了九个月的抗结核治疗,但动眼神经功能仅部分恢复。

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本文引用的文献

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Solitary Sign of Third Nerve Palsy in a Conscious Patient With Epidural Hemorrhage.清醒的硬膜外出血患者出现动眼神经麻痹的孤立体征。
Cureus. 2020 Aug 24;12(8):e10003. doi: 10.7759/cureus.10003.
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Isolated bilateral partial third nerve palsy due to large midbrain tuberculoma.孤立性双侧部分动眼神经麻痹由大脑中脑巨大结核瘤所致。
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Clinical characteristics of tuberculous meningitis combined with cranial nerve palsy.结核性脑膜炎合并脑神经麻痹的临床特征
Clin Neurol Neurosurg. 2019 Sep;184:105443. doi: 10.1016/j.clineuro.2019.105443. Epub 2019 Jul 15.
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Acute Bilateral Oculomotor Nerve Palsy in an Adult Patient with Neisseria meningitidis.一名成年脑膜炎奈瑟菌患者出现急性双侧动眼神经麻痹
Intern Med. 2019 Jun 1;58(11):1639-1642. doi: 10.2169/internalmedicine.2098-18. Epub 2019 Feb 1.
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