Kisser W
Arch Toxicol. 1977 Jul 19;37(3):173-93. doi: 10.1007/BF00355487.
After a short description of sources of lead poisoning a review is given of toxicity, absorption, storage and excretion of lead. Afterwards its biochemical affects--especially the influence on the biosynthesis of heme--are treated. Methods for diagnosis of lead poisoning resulting from these affects--determination of coproporphyrine and delta-aminolevulinic acid excretion in urine, erythrocyte delta-aminolevulinic acid dehydratase activity and erythrocyte protoporphyrin--are discussed in detail.
在简短描述铅中毒的来源之后,本文对铅的毒性、吸收、储存和排泄进行了综述。随后探讨了其生化影响——尤其是对血红素生物合成的影响。详细讨论了由这些影响导致的铅中毒的诊断方法——尿中粪卟啉和δ-氨基乙酰丙酸排泄量的测定、红细胞δ-氨基乙酰丙酸脱水酶活性以及红细胞原卟啉。